Vecuronium Bromide | CAS#50700-72-6 | Muscle Relaxant

MedKoo Cat#: 318975 | Name: Vecuronium bromide

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Vecuronium bromide is a muscle relaxant in the category of non-depolarizing blocking agents. Vecuronium bromide is indicated as an adjunct to general anesthesia, to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation. Although vecuronium bromide is often thought of as a muscle relaxant, it may be more accurate to classify it as a paralyzing agent. Vecuronium's structure is derived from the same aminosteroid structure as pancuronium, but it is missing the methyl group on the piperidine nitrogen that is attached to the 'A' ring, making it monoquaternary, like D-tubocurarine. It has the same configuration at all ten stereocentres as pancuronium, and is a single-isomer preparation.

Chemical Structure

Vecuronium bromide

CAS#50700-72-6

Theoretical Analysis

MedKoo Cat#: 318975

Name: Vecuronium bromide

CAS#: 50700-72-6

Chemical Formula: C34H57BrN2O4

Exact Mass: 0.0000

Molecular Weight: 637.74

Elemental Analysis: C, 64.03; H, 9.01; Br, 12.53; N, 4.39; O, 10.03

Price and Availability

Size	Price	Availability
200mg	USD 950.00	2 Weeks
500mg	USD 1,650.00	2 Weeks
1g	USD 2,950.00	2 Weeks

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Related CAS #

No Data

Synonym

NC 45; NC-45; NC45; ORG NC 45; ORG NC45; ORG-NC 45; ORG-NC-45; ORG-NC45; ORGNC 45; ORGNC45; Vecuronium bromide. Brand name Norcuron.

IUPAC/Chemical Name

1-((2S,3S,5S,8R,9S,10S,13S,14S,16S,17S)-3,17-diacetoxy-10,13-dimethyl-2-(piperidin-1-yl)hexadecahydro-1H-cyclopenta[a]phenanthren-16-yl)-1-methylpiperidin-1-ium bromide

InChi Key

VEPSYABRBFXYIB-WSIGYWTFSA-M

InChi Code

InChI=1S/C34H57N2O4.BrH/c1-23(37)39-31-20-25-12-13-26-27(34(25,4)22-29(31)35-16-8-6-9-17-35)14-15-33(3)28(26)21-30(32(33)40-24(2)38)36(5)18-10-7-11-19-36;/h25-32H,6-22H2,1-5H3;1H/q+1;/p-1/t25-,26+,27-,28-,29-,30-,31-,32+,33-,34-;/m0./s1

SMILES Code

CC(O[C@@H]1[C@@H](N2CCCCC2)C[C@]3(C)[C@@]4([H])CC[C@]5(C)[C@H](OC(C)=O)[C@@H]([N+]6(C)CCCCC6)C[C@@]5([H])[C@]4([H])CC[C@@]3([H])C1)=O.[Br-]

Appearance

White to off-white crystalline powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO, not in water

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 637.74 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

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