Boldine is an alkaloid of the aporphine class that can be found in the boldo tree and in Lindera aggregata. Boldine has antioxidant activity that effectively protects against free radical induced lipid peroxidation or enzyme inactivation. In addition, it has alpha-adrenergic antagonist activities in vascular tissue, and it has also been reported to have hepatoprotective, cytoprotective, antipyretic and anti-inflammatory effects.
MedKoo Cat#: 600118
Name: Boldine
CAS#: 476-70-0
Chemical Formula: C19H21NO4
Exact Mass: 327.1471
Molecular Weight: 327.37
Elemental Analysis: C, 69.71; H, 6.47; N, 4.28; O, 19.55
| Solvent | mg/mL | mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 71.7 | 218.93 | |
| DMSO:PBS (pH 7.2) (1:1) | 0.5 | 1.53 | |
| DMF | 50.0 | 152.73 | |
| Ethanol | 30.0 | 91.64 |
The following data is based on the product molecular weight 327.37 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
