MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 510218 | Name: dCTP

Description:

WARNING: This product is for research use only, not for human or veterinary use.

dCTP is also know as 2'-Deoxycytidine-5'-triphosphate trisodium salt.

Chemical Structure

dCTP
dCTP
CAS#109909-44-6

Theoretical Analysis

MedKoo Cat#: 510218

Name: dCTP

CAS#: 109909-44-6

Chemical Formula: C9H16N3O13P3

Exact Mass: 466.9896

Molecular Weight: 467.16

Elemental Analysis: C, 23.14; H, 3.45; N, 8.99; O, 44.52; P, 19.89

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
dCTP Thymus; Cytidine 5(tetrahydrogen triphosphate) 2deoxy trisodium salt; Cytidine 2deoxy 5(tetrahydrogen triphosphate) trisodium salt; Cytidine 2deoxy triphosphate trisodium salt; 2DeoxyCTP trisodium salt; 2Deoxycytidine 5triphosphate trisodium salt; 5DCTP trisodium salt; Deoxy5CTPtrisodium salt; DeoxyCTP trisodium salt; Deoxycytidine 5triphosphate trisodium salt; Deoxycytidine triphosphate trisodium salt.
IUPAC/Chemical Name
sodium ((2R,3S,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl hydrogentriphosphate
InChi Key
WBIPTAOOMJEGQO-MILVPLDLSA-K
InChi Code
InChI=1S/C9H16N3O13P3.3Na/c10-7-1-2-12(9(14)11-7)8-3-5(13)6(23-8)4-22-27(18,19)25-28(20,21)24-26(15,16)17;;;/h1-2,5-6,8,13H,3-4H2,(H,18,19)(H,20,21)(H2,10,11,14)(H2,15,16,17);;;/q;3*+1/p-3/t5-,6+,8+;;;/m0.../s1
SMILES Code
O[C@@H](C[C@H](N1C(N=C(C=C1)N)=O)O2)[C@H]2COP(OP(OP(O)(O[Na])=O)(O[Na])=O)(O[Na])=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO, not in water
Shelf Life
>5 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
         

Preparing Stock Solutions

The following data is based on the product molecular weight 467.16 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Kewn S, Hoggard PG, Sales SD, Johnson MA, Back DJ. The intracellular activation of lamivudine (3TC) and determination of 2'-deoxycytidine-5'-triphosphate (dCTP) pools in the presence and absence of various drugs in HepG2 cells. Br J Clin Pharmacol. 2000 Dec;50(6):597-604. PubMed PMID: 11136299; PubMed Central PMCID: PMC2015020. 2: Nonaka M, Tsuchimoto D, Sakumi K, Nakabeppu Y. Mouse RS21-C6 is a mammalian 2'-deoxycytidine 5'-triphosphate pyrophosphohydrolase that prefers 5-iodocytosine. FEBS J. 2009 Mar;276(6):1654-66. doi: 10.1111/j.1742-4658.2009.06898.x. Epub 2009 Feb 7. PubMed PMID: 19220460. 3: Zhang H, Wood OL, Papermaster SF, Nielsen CJ, Ussery MA. Palindromic oligonucleotide-directed enzymatic determination of 2'-deoxythymidine 5'-triphosphate and 2'-deoxycytidine 5'-triphosphate in human cells. Anal Biochem. 1997 Oct 1;252(1):143-52. PubMed PMID: 9324952. 4: Piall EM, Aherne GW, Marks V. The quantitative determination of 2'-deoxycytidine-5'-triphosphate in cell extracts by radioimmunoassay. Anal Biochem. 1986 Apr;154(1):276-81. PubMed PMID: 3010772. 5: Danks MK. Two simple high-performance liquid chromatographic methods for simultaneous determination of 2'-deoxycytidine 5'-triphosphate and cytosine arabinoside 5'-triphosphate concentrations in biological samples. J Chromatogr. 1982 Dec 10;233:141-8. PubMed PMID: 7161328. 6: Sagar P, Kára J. Activation of deoxycytidylate deaminase from certain embryonal and tumour tissues by 6-aza-2'-deoxycytidine-5'-monophosphate and 2'-deoxycytidine-5'-triphosphate. Folia Biol (Praha). 1966;12(1):75-9. PubMed PMID: 4288008.