Synonym
AB-05831; AB 05831; AB05831; 2-ADN; DGJNAc; 2-Acetamido-1,2-dideoxynojirimycin; 1,2-dideoxy-2-Nacetamidonojirimycin; 2-Acetamido-1,5-imino-1,2,5-trideoxy-Dglucitol; PubChem ID170506941.
IUPAC/Chemical Name
N-((3S,4R,5R,6R)-4,5-dihydroxy-6-(hydroxymethyl)piperidin-3-yl)acetamide
InChi Key
GBRAQQUMMCVTAV-LXGUWJNJSA-N
InChi Code
InChI=1S/C8H16N2O4/c1-4(12)10-5-2-9-6(3-11)8(14)7(5)13/h5-9,11,13-14H,2-3H2,1H3,(H,10,12)/t5-,6+,7+,8+/m0/s1
SMILES Code
CC(N[C@H]1CN[C@H](CO)[C@@H](O)[C@@H]1O)=O
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO, not in water
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
204.22
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
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7: Butters TD, Scudder P, Rotsaert J, Petursson S, Fleet GW, Willenbrock FW, Jacob GS. Purification to homogeneity of Charonia lampas alpha-fucosidase by using sequential ligand-affinity chromatography. Biochem J. 1991 Oct 1;279 ( Pt 1):189-95. PubMed PMID: 1930138; PubMed Central PMCID: PMC1151565.
8: Nagahashi G, Tu SI, Fleet G, Namgoong SK. Inhibition of cell wall-associated enzymes in vitro and in vivo with sugar analogs. Plant Physiol. 1990 Feb;92(2):413-8. PubMed PMID: 16667291; PubMed Central PMCID: PMC1062307.
9: Böshagen H, Heiker FR, Schüller AM. The chemistry of the 1-deoxynojirimycin system. Synthesis of 2-acetamido-1,2-dideoxynojirimycin from 1-deoxynojirimycin. Carbohydr Res. 1987 Jul 1;164:141-8. PubMed PMID: 2957054.
