MedKoo Cat#: 510339 | Name: PTZ-343
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

PTZ-343 is a phenothiazine (PTZ) derivative with chemical name sodium 3-(10H-phenothiazin-10-yl)propane-1-sulfonate. The free acid of PTZ-343 has molecule weight 343. For the convenience of commucation, we call it as PTZ-343. PTZ-343 is a water-soluble enhancer of luminol chemiluminescent peroxidation catalyzed by horseradish peroxidase (HRP). It acts as an electron transfer mediator, reacting with HRP-II to release HRP and a PTZ-343 radical, which oxidizes luminol anions to induce light emission.

Chemical Structure

PTZ-343
PTZ-343
CAS#101199-38-6 (sodium)

Theoretical Analysis

MedKoo Cat#: 510339

Name: PTZ-343

CAS#: 101199-38-6 (sodium)

Chemical Formula: C15H14NNaO3S2

Exact Mass: 0.0000

Molecular Weight: 343.39

Elemental Analysis: C, 52.46; H, 4.11; N, 4.08; Na, 6.69; O, 13.98; S, 18.68

Price and Availability

Size Price Availability Quantity
1g USD 85.00 Ready to ship
5g USD 350.00 Ready to ship
10g USD 550.00 Ready to ship
25g USD 1,150.00 Ready to ship
50g USD 2,050.00 Ready to ship
100g USD 3,650.00 Ready to ship
500g USD 6,950.00 2 Weeks
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Related CAS #
101199-38-6 (sodium) 129808-92-0 (free acid)
Synonym
PTZ343; PTZ 343; PTZ-343; PTZ-343 sodium.
IUPAC/Chemical Name
sodium 3-(10H-phenothiazin-10-yl)propane-1-sulfonate
InChi Key
VKGYKXFNSKEHED-UHFFFAOYSA-M
InChi Code
InChI=1S/C15H15NO3S2.Na/c17-21(18,19)11-5-10-16-12-6-1-3-8-14(12)20-15-9-4-2-7-13(15)16;/h1-4,6-9H,5,10-11H2,(H,17,18,19);/q;+1/p-1
SMILES Code
O=S(CCCN1C2=C(C=CC=C2)SC3=CC=CC=C13)([O-])=O.[Na+]
Appearance
White solid powder
Purity
>95% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO, not in water
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 343.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Marzocchi, E.,Grilli, S.,Della Ciana, L., et al. Chemiluminescent detection systems of horseradish peroxidase employing nucleophilic acylation catalysts. Anal. Biochem. 377(2), 189-194 (2008). 2. Vdovenko, M.M.,Della Ciana, L. and Sakharov, I.Y. 3-(100-Phenothiazinyl)propane-1-sulfonate is a potent enhancer of soybean peroxidase-induced chemiluminescence. Anal. Biochem. 392(1), 54-58 (2009). 3. Masato. Sakaguchi , Ming. Hu , Larry. Kevan. Photoionization of alkylphenothiazines in vesicles: effects of the alkyl chain length and the vesicle surface charge. J. Phys. Chem., 1990, 94 (2), pp 870–874.