MedKoo Cat#: 315229 | Name: Lacosamide

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Lacosamide, also known as ADD 243037 and SPM 927, is a medication developed by UCB for the adjunctive treatment of partial-onset seizures and diabetic neuropathic pain marketed under the trade name Vimpat. Lacosamide is discontinued (DEA controlled substance).

Chemical Structure

Lacosamide
Lacosamide
CAS#175481-36-4

Theoretical Analysis

MedKoo Cat#: 315229

Name: Lacosamide

CAS#: 175481-36-4

Chemical Formula: C13H18N2O3

Exact Mass: 250.1317

Molecular Weight: 250.20

Elemental Analysis: C, 62.38; H, 7.25; N, 11.19; O, 19.18

Price and Availability

This product was removed for the commercial reasons.
Related CAS #
No Data
Synonym
Vimpat; erlosamide; ADD 243037; SPM 927; ADD243037; SPM927; ADD-243037; SPM-927.
IUPAC/Chemical Name
(R)-2-acetamido-N-benzyl-3-methoxypropionamide.
InChi Key
VPPJLAIAVCUEMN-GFCCVEGCSA-N
InChi Code
InChI=1S/C13H18N2O3/c1-10(16)15-12(9-18-2)13(17)14-8-11-6-4-3-5-7-11/h3-7,12H,8-9H2,1-2H3,(H,14,17)(H,15,16)/t12-/m1/s1
SMILES Code
O=C(NCC1=CC=CC=C1)[C@H](NC(C)=O)COC
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO.
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 250.20 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Hawkes MA, Fernández Suárez M, Ugarnes G, D'Giano C. Single-dose oral lacosamide in refractory simple partial status epilepticus: case report and review. Clin Neuropharmacol. 2013 Jul-Aug;36(4):138-40. doi: 10.1097/WNF.0b013e31829b21ba. Review. PubMed PMID: 23860347.