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MedKoo Cat#: 129092 | Name: EU1622-240

Description:

WARNING: This product is for research use only, not for human or veterinary use.

EU1622-240 is a NMDAR modulator.

Chemical Structure

EU1622-240
EU1622-240
CAS#3057728-22-7

Theoretical Analysis

MedKoo Cat#: 129092

Name: EU1622-240

CAS#: 3057728-22-7

Chemical Formula: C20H14BrF2N3O2S

Exact Mass: 476.9958

Molecular Weight: 478.31

Elemental Analysis: C, 50.22; H, 2.95; Br, 16.71; F, 7.94; N, 8.79; O, 6.69; S, 6.70

Price and Availability

Related CAS #
No Data
Synonym
EU1622-240; EU1622240; EU1622 240
IUPAC/Chemical Name
5-(3-bromo-4-fluorophenyl)-6-ethynyl-3-(2-(3-fluoro-3-methylazetidin-1-yl)-2-oxoethyl)thieno[2,3-d]pyrimidin-4(3H)-one
InChi Key
YKNBSYYYBWQJQW-UHFFFAOYSA-N
InChi Code
InChI=1S/C20H14BrF2N3O2S/c1-3-14-16(11-4-5-13(22)12(21)6-11)17-18(29-14)24-10-25(19(17)28)7-15(27)26-8-20(2,23)9-26/h1,4-6,10H,7-9H2,2H3
SMILES Code
C#CC1=C(C2=C(N=CN(C2=O)CC(N3CC(F)(C3)C)=O)S1)C4=CC=C(C(Br)=C4)F
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 478.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

Ullman EZ, Perszyk RE, Paladugu S, Fritzemeier RG, Akins NS, Jacobs L, Liotta DC, Traynelis SF. Mechanisms of Action Underlying Conductance-Modifying Positive Allosteric Modulators of the NMDA Receptor. Mol Pharmacol. 2024 Nov 18;106(6):334-353. doi: 10.1124/molpharm.124.001019. PMID: 39443157; PMCID: PMC11585258.