MedKoo Cat#: 129043 | Name: CT1113
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

CT1113 is a potent dual inhibitor of USP25 and USP28 that effectively reduces c-MYC levels and exhibits strong anti-tumor activity.

Chemical Structure

CT1113
CT1113
CAS#2523435-18-7

Theoretical Analysis

MedKoo Cat#: 129043

Name: CT1113

CAS#: 2523435-18-7

Chemical Formula: C25H29N5O2S

Exact Mass: 463.2042

Molecular Weight: 463.60

Elemental Analysis: C, 64.77; H, 6.31; N, 15.11; O, 6.90; S, 6.92

Price and Availability

Size Price Availability Quantity
5mg USD 550.00 2 Weeks
25mg USD 950.00 2 Weeks
100mg USD 1,650.00 2 Weeks
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Related CAS #
No Data
Synonym
CT1113; CT-1113; CT 1113
IUPAC/Chemical Name
N-((3R)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)chroman-3-yl)-6-methyl-3-(methylamino)thieno[2,3-b]pyridine-2-carboxamide
InChi Key
WTGNDKCABSWCMB-DAWZGUTISA-N
InChi Code
InChI=1S/C25H29N5O2S/c1-14-3-8-20-22(26-2)23(33-25(20)27-14)24(31)29-18-9-15-4-7-19(10-21(15)32-13-18)30-11-16-5-6-17(12-30)28-16/h3-4,7-8,10,16-18,26,28H,5-6,9,11-13H2,1-2H3,(H,29,31)/t16?,17?,18-/m1/s1
SMILES Code
CNC1=C(C(N[C@@H]2CC3=CC=C(N4CC5NC(CC5)C4)C=C3OC2)=O)SC6=NC(C)=CC=C16
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 463.60 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Peng J, Jiang K, Sun X, Wu L, Wang J, Xi X, Tan X, Liang T, Tan C, Zhang P. Identification of a class of potent USP25/28 inhibitors with broad-spectrum anti-cancer activity. Signal Transduct Target Ther. 2022 Dec 8;7(1):393. doi: 10.1038/s41392-022-01209-2. PMID: 36481755; PMCID: PMC9731946.