MedKoo Cat#: 129009 | Name: VUF26034

Description:

WARNING: This product is for research use only, not for human or veterinary use.

VUF26034 is a β2-AR agonist. VUF26034 has suitable photochemical properties and good thermal stability of the cis isomer (t1/2 ∼ 4months), switching from a partial agonist to a >25-fold higher affinity antagonist upon illumination with 360 nm.

Chemical Structure

VUF26034
VUF26034
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 129009

Name: VUF26034

CAS#: N/A

Chemical Formula: C18H21Cl2N3O

Exact Mass: 365.1062

Molecular Weight: 366.29

Elemental Analysis: C, 59.02; H, 5.78; Cl, 19.36; N, 11.47; O, 4.37

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
VUF26034; VUF-26034; VUF 26034
IUPAC/Chemical Name
(E)-2-(tert-butylamino)-1-(3,5-dichloro-4-(phenyldiazenyl)phenyl)ethan-1-ol
InChi Key
BKBQAPKNQMIKDI-GHVJWSGMSA-N
InChi Code
InChI=1S/C18H21Cl2N3O/c1-18(2,3)21-11-16(24)12-9-14(19)17(15(20)10-12)23-22-13-7-5-4-6-8-13/h4-10,16,21,24H,11H2,1-3H3/b23-22+
SMILES Code
ClC1=C(C(Cl)=CC(C(O)CNC(C)(C)C)=C1)/N=N/C2=CC=CC=C2
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 366.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Cao Y, Shi S, Does SAH, Buzink CML, Gao M, de Esch IJP, Vischer HF, Wijtmans M, Leurs R. Photo-clenbuterol: Optical Control of β2-Adrenergic Receptor Signaling by Photoswitchable Ligand Efficacy. J Med Chem. 2025 Jun 10. doi: 10.1021/acs.jmedchem.5c00792. Epub ahead of print. PMID: 40492834.