MedKoo Cat#: 128986 | Name: KC159
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

KC159 is an agonist of Piezo1.

Chemical Structure

KC159
KC159
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 128986

Name: KC159

CAS#: N/A

Chemical Formula: C16H10Cl2N2O2S2

Exact Mass: 395.9561

Molecular Weight: 397.29

Elemental Analysis: C, 48.37; H, 2.54; Cl, 17.85; N, 7.05; O, 8.05; S, 16.14

Price and Availability

Size Price Availability Quantity
1mg USD 350.00 2 Weeks
5mg USD 650.00 2 Weeks
10mg USD 1,050.00 2 Weeks
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Related CAS #
No Data
Synonym
KC159; KC 159; KC-159
IUPAC/Chemical Name
4-(5-((2,6-dichlorobenzyl)thio)-1,3,4-thiadiazol-2-yl)benzoic acid
InChi Key
KFIUJWYVLYQUOY-UHFFFAOYSA-N
InChi Code
InChI=1S/C16H10Cl2N2O2S2/c17-12-2-1-3-13(18)11(12)8-23-16-20-19-14(24-16)9-4-6-10(7-5-9)15(21)22/h1-7H,8H2,(H,21,22)
SMILES Code
O=C(O)C1=CC=C(C2=NN=C(SCC3=C(Cl)C=CC=C3Cl)S2)C=C1
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 397.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Parsonage, G., Cuthbertson, K., Endesh, N., et al. Improved PIEZO1 agonism through 4-benzoic acid modification of Yoda1. Br. J. Pharmacol. 180(16), 2039-2063 (2023).