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MedKoo Cat#: 128980 | Name: Ac-RGK(Ac)-AMC (acetate)
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Ac-RGK(Ac)-AMC is a fluorogenic substrate for histone deacetylases (HDACs).

Chemical Structure

Ac-RGK(Ac)-AMC (acetate)
Ac-RGK(Ac)-AMC (acetate)
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 128980

Name: Ac-RGK(Ac)-AMC (acetate)

CAS#: N/A

Chemical Formula: C30H44N8O9

Exact Mass: 660.3231

Molecular Weight: 660.73

Elemental Analysis: C, 54.54; H, 6.71; N, 16.96; O, 21.79

Price and Availability

Size Price Availability Quantity
1mg USD 350.00 2 Weeks
5mg USD 650.00 2 Weeks
10mg USD 950.00 2 Weeks
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Related CAS #
No Data
Synonym
Ac-RGK(Ac)-AMC; Ac-RGK(Ac)-AMC (acetate); Ac-Arg-Gly-Lys(Ac)-AMC
IUPAC/Chemical Name
(S)-6-acetamido-2-(2-((S)-2-acetamido-5-guanidinopentanamido)acetamido)-N-(4-methyl-2-oxo-2H-chromen-7-yl)hexanamide acetate
InChi Key
JWMWFKSBFSCIFY-VROPFNGYSA-N
InChi Code
InChI=1S/C28H40N8O7.C2H4O2/c1-16-13-25(40)43-23-14-19(9-10-20(16)23)35-27(42)22(7-4-5-11-31-17(2)37)36-24(39)15-33-26(41)21(34-18(3)38)8-6-12-32-28(29)30;1-2(3)4/h9-10,13-14,21-22H,4-8,11-12,15H2,1-3H3,(H,31,37)(H,33,41)(H,34,38)(H,35,42)(H,36,39)(H4,29,30,32);1H3,(H,3,4)/t21-,22-;/m0./s1
SMILES Code
NC(NCCC[C@H](NC(C)=O)C(NCC(N[C@@H](CCCCNC(C)=O)C(NC1=CC=C(C(C)=CC(O2)=O)C2=C1)=O)=O)=O)=N.CC(O)=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 660.73 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Wegener, D., Wirsching, F., Riester, D., et al. A fluorogenic histone deacetylase assay well suited for high-throughput activity screening. Chem. Biol. 10(1), 61-68 (2003).

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AKB-4924

AKB-4924