Zidapamide is a thiazide-like diuretic used primarily for the treatment of hypertension and, in some cases, edema associated with heart failure or renal disorders. It works by inhibiting sodium and chloride reabsorption in the distal convoluted tubules of the kidney, promoting diuresis and leading to a reduction in blood volume and blood pressure. Zidapamide may also exhibit some vasodilatory effects, contributing further to its antihypertensive action.
MedKoo Cat#: 146386
Name: Zidapamide
CAS#: 75820-08-5
Chemical Formula: C16H16ClN3O3S
Exact Mass: 365.0601
Molecular Weight: 365.83
Elemental Analysis: C, 52.53; H, 4.41; Cl, 9.69; N, 11.49; O, 13.12; S, 8.76
The following data is based on the product molecular weight 365.83 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
