Lycopene | CAS#502-65-8 | cartenoid

MedKoo Cat#: 146377 | Name: Lycopene

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Lycopene is a naturally occurring carotenoid pigment found in tomatoes and other red fruits and vegetables. It functions as a powerful antioxidant, neutralizing free radicals and helping to protect cells from oxidative damage. Lycopene is studied for its potential role in reducing the risk of certain chronic diseases, including cardiovascular disease and some cancers.

Chemical Structure

Lycopene

CAS#502-65-8

Theoretical Analysis

MedKoo Cat#: 146377

Name: Lycopene

CAS#: 502-65-8

Chemical Formula: C40H56

Exact Mass: 536.4382

Molecular Weight: 536.89

Elemental Analysis: C, 89.49; H, 10.51

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Lycopene;

IUPAC/Chemical Name

(6E,8E,10E,12E,14E,16E,18E,20E,22E,24E,26E)-2,6,10,14,19,23,27,31-octamethyldotriaconta-2,6,8,10,12,14,16,18,20,22,24,26,30-tridecaene

InChi Key

OAIJSZIZWZSQBC-GYZMGTAESA-N

InChi Code

1S/C40H56/c1-33(2)19-13-23-37(7)27-17-31-39(9)29-15-25-35(5)21-11-12-22-36(6)26-16-30-40(10)32-18-28-38(8)24-14-20-34(3)4/h11-12,15-22,25-32H,13-14,23-24H2,1-10H3/b12-11+,25-15+,26-16+,31-17+,32-18+,35-21+,36-22+,37-27+,38-28+,39-29+,40-30+

SMILES Code

CC(C)=CCC\C(C)=C\C=C\C(C)=C\C=C\C(C)=C\C=C\C=C(C)\C=C\C=C(C)\C=C\C=C(/C)CCC=C(C)C

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 536.89 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Khan UM, Sevindik M, Zarrabi A, Nami M, Ozdemir B, Kaplan DN, Selamoglu Z, Hasan M, Kumar M, Alshehri MM, Sharifi-Rad J. Lycopene: Food Sources, Biological Activities, and Human Health Benefits. Oxid Med Cell Longev. 2021 Nov 19;2021:2713511. doi: 10.1155/2021/2713511. PMID: 34840666; PMCID: PMC8626194. 2: Przybylska S, Tokarczyk G. Lycopene in the Prevention of Cardiovascular Diseases. Int J Mol Sci. 2022 Feb 10;23(4):1957. doi: 10.3390/ijms23041957. PMID: 35216071; PMCID: PMC8880080. 3: Li N, Wu X, Zhuang W, Xia L, Chen Y, Wu C, Rao Z, Du L, Zhao R, Yi M, Wan Q, Zhou Y. Tomato and lycopene and multiple health outcomes: Umbrella review. Food Chem. 2021 May 1;343:128396. doi: 10.1016/j.foodchem.2020.128396. Epub 2020 Oct 15. PMID: 33131949. 4: Moran NE, Thomas-Ahner JM, Wan L, Zuniga KE, Erdman JW, Clinton SK. Tomatoes, Lycopene, and Prostate Cancer: What Have We Learned from Experimental Models? J Nutr. 2022 Jun 9;152(6):1381-1403. doi: 10.1093/jn/nxac066. PMID: 35278075; PMCID: PMC9178968. 5: Mirahmadi M, Azimi-Hashemi S, Saburi E, Kamali H, Pishbin M, Hadizadeh F. Potential inhibitory effect of lycopene on prostate cancer. Biomed Pharmacother. 2020 Sep;129:110459. doi: 10.1016/j.biopha.2020.110459. Epub 2020 Jun 30. PMID: 32768949. 6: Kapała A, Szlendak M, Motacka E. The Anti-Cancer Activity of Lycopene: A Systematic Review of Human and Animal Studies. Nutrients. 2022 Dec 3;14(23):5152. doi: 10.3390/nu14235152. PMID: 36501182; PMCID: PMC9741066. 7: Crowe-White KM, Phillips TA, Ellis AC. Lycopene and cognitive function. J Nutr Sci. 2019 May 29;8:e20. doi: 10.1017/jns.2019.16. PMID: 31217968; PMCID: PMC6558668. 8: Zhu R, Chen B, Bai Y, Miao T, Rui L, Zhang H, Xia B, Li Y, Gao S, Wang XD, Zhang D. Lycopene in protection against obesity and diabetes: A mechanistic review. Pharmacol Res. 2020 Sep;159:104966. doi: 10.1016/j.phrs.2020.104966. Epub 2020 Jun 12. PMID: 32535223. 9: Zhao Z, Liu Z, Mao X. Biotechnological Advances in Lycopene β-Cyclases. J Agric Food Chem. 2020 Oct 28;68(43):11895-11907. doi: 10.1021/acs.jafc.0c04814. Epub 2020 Oct 19. PMID: 33073992. 10: Khongthaw B, Dulta K, Chauhan PK, Kumar V, Ighalo JO. Lycopene: a therapeutic strategy against coronavirus disease 19 (COVID- 19). Inflammopharmacology. 2022 Dec;30(6):1955-1976. doi: 10.1007/s10787-022-01061-4. Epub 2022 Sep 1. PMID: 36050507; PMCID: PMC9436159. 11: Vakili S, Samare-Najaf M, Karimi A, Jahromi BN, Mohit M, Hashempur MH. Lycopene in male infertility. Naunyn Schmiedebergs Arch Pharmacol. 2025 May;398(5):4817-4835. doi: 10.1007/s00210-024-03520-x. Epub 2024 Dec 10. PMID: 39656221. 12: Kapoor B, Gulati M, Rani P, Kochhar RS, Atanasov AG, Gupta R, Sharma D, Kapoor D. Lycopene: Sojourn from kitchen to an effective therapy in Alzheimer's disease. Biofactors. 2023 Mar;49(2):208-227. doi: 10.1002/biof.1910. Epub 2022 Nov 1. PMID: 36318372. 13: Senkus KE, Tan L, Crowe-White KM. Lycopene and Metabolic Syndrome: A Systematic Review of the Literature. Adv Nutr. 2019 Jan 1;10(1):19-29. doi: 10.1093/advances/nmy069. PMID: 30475939; PMCID: PMC6370260. 14: Khalaf RA, Awad M. Lycopene as a Potential Bioactive Compound: Chemistry, Extraction, and Anticancer Prospective. Curr Cancer Drug Targets. 2023;23(8):634-642. doi: 10.2174/1568009623666230131124236. PMID: 36718971. 15: Leh HE, Lee LK. Lycopene: A Potent Antioxidant for the Amelioration of Type II Diabetes Mellitus. Molecules. 2022 Apr 4;27(7):2335. doi: 10.3390/molecules27072335. PMID: 35408734; PMCID: PMC9000630. 16: Li L, Liu Z, Jiang H, Mao X. Biotechnological production of lycopene by microorganisms. Appl Microbiol Biotechnol. 2020 Dec;104(24):10307-10324. doi: 10.1007/s00253-020-10967-4. Epub 2020 Oct 24. PMID: 33097966. 17: Wu S, Guo X, Shang J, Li Y, Dong W, Peng Q, Xie Z, Chen C. Effects of Lycopene Attenuating Injuries in Ischemia and Reperfusion. Oxid Med Cell Longev. 2022 Oct 7;2022:9309327. doi: 10.1155/2022/9309327. PMID: 36246396; PMCID: PMC9568330. 18: Paul R, Mazumder MK, Nath J, Deb S, Paul S, Bhattacharya P, Borah A. Lycopene - A pleiotropic neuroprotective nutraceutical: Deciphering its therapeutic potentials in broad spectrum neurological disorders. Neurochem Int. 2020 Nov;140:104823. doi: 10.1016/j.neuint.2020.104823. Epub 2020 Aug 20. PMID: 32827559. 19: Ozkan G, Günal-Köroğlu D, Karadag A, Capanoglu E, Cardoso SM, Al-Omari B, Calina D, Sharifi-Rad J, Cho WC. A mechanistic updated overview on lycopene as potential anticancer agent. Biomed Pharmacother. 2023 May;161:114428. doi: 10.1016/j.biopha.2023.114428. Epub 2023 Feb 24. PMID: 36841029. 20: Pan X, Zhu R, Pei J, Zhang L. Lycopene: A potent antioxidant to alleviate kidney disease. Int Immunopharmacol. 2025 Apr 4;151:114363. doi: 10.1016/j.intimp.2025.114363. Epub 2025 Mar 1. PMID: 40022820.