MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 146370 | Name: Carvacrol

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Carvacrol is a natural monoterpenoid phenol primarily found in oregano (Origanum vulgare) and thyme oils, known for its strong antimicrobial, antifungal, and antioxidant properties. It is widely used in food preservation, animal feed, pharmaceuticals, and cosmetics for its ability to inhibit the growth of harmful microorganisms. Carvacrol exerts its effects by disrupting bacterial cell membranes, altering membrane permeability, and interfering with essential cell functions.

Chemical Structure

Carvacrol
Carvacrol
CAS#499-75-2

Theoretical Analysis

MedKoo Cat#: 146370

Name: Carvacrol

CAS#: 499-75-2

Chemical Formula: C10H14O

Exact Mass: 150.1045

Molecular Weight: 150.22

Elemental Analysis: C, 79.96; H, 9.39; O, 10.65

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
Carvacrol;
IUPAC/Chemical Name
5-isopropyl-2-methylphenol
InChi Key
RECUKUPTGUEGMW-UHFFFAOYSA-N
InChi Code
1S/C10H14O/c1-7(2)9-5-4-8(3)10(11)6-9/h4-7,11H,1-3H3
SMILES Code
CC(C)C1=CC(O)=C(C)C=C1
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 150.22 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Singh J, Luqman S, Meena A. Carvacrol as a Prospective Regulator of Cancer Targets/Signalling Pathways. Curr Mol Pharmacol. 2023 Mar 27;16(5):542-558. doi: 10.2174/1874467215666220705142954. PMID: 35792130. 2: Hoca M, Becer E, Vatansever HS. Carvacrol is potential molecule for diabetes treatment. Arch Physiol Biochem. 2024 Dec;130(6):823-830. doi: 10.1080/13813455.2023.2288537. Epub 2023 Nov 29. PMID: 38019023. 3: Peter S, Sotondoshe N, Aderibigbe BA. Carvacrol and Thymol Hybrids: Potential Anticancer and Antibacterial Therapeutics. Molecules. 2024 May 12;29(10):2277. doi: 10.3390/molecules29102277. PMID: 38792138; PMCID: PMC11123974. 4: El Boukhari R, Fatimi A. Carvacrol: Innovative Synthesis Pathways and Overview of its Patented Applications. Recent Pat Biotechnol. 2025;19(1):53-68. doi: 10.2174/0118722083292888240223094707. PMID: 39840411. 5: Anwar S, Khan AU, Irshad N. Pharmacological evaluation of carvacrol anti- migraine potential. Naunyn Schmiedebergs Arch Pharmacol. 2023 Jun;396(6):1309-1324. doi: 10.1007/s00210-023-02412-w. Epub 2023 Feb 1. PMID: 36723608. 6: Zhang S, He L, Shang J, Chen L, Xu Y, Chen X, Li X, Jiao Q, Jin S, Hu X, Liang W. Carvacrol Suppresses Human Osteosarcoma Cells via the Wnt/β-Catenin Signaling Pathway. Anticancer Agents Med Chem. 2022;22(9):1714-1722. doi: 10.2174/1871520621666210901111932. PMID: 34488595. 7: Cardoso LT, Alexandre B, Cacciatore FA, Magedans YVDS, Fett-Neto AG, Contri RV, Malheiros PDS. Carvacrol-loaded nanoemulsions produced with a natural emulsifier for lettuce sanitization. Food Res Int. 2023 Jun;168:112748. doi: 10.1016/j.foodres.2023.112748. Epub 2023 Mar 22. PMID: 37120202. 8: Liu Q, Qiao K, Zhang S. Potential of a Small Molecule Carvacrol in Management of Vegetable Diseases. Molecules. 2019 May 20;24(10):1932. doi: 10.3390/molecules24101932. PMID: 31137465; PMCID: PMC6572147. 9: Silva ER, de Carvalho FO, Teixeira LGB, Santos NGL, Felipe FA, Santana HSR, Shanmugam S, Quintans Júnior LJ, de Souza Araújo AA, Nunes PS. Pharmacological Effects of Carvacrol in In vitro Studies: A Review. Curr Pharm Des. 2018 Dec 8;24(29):3454-3465. doi: 10.2174/1381612824666181003123400. PMID: 30280662. 10: Kutlu T, Güvenç M. Effects of carvacrol on experimental nephrolithiasis in female rats. Biotech Histochem. 2023 Jan;98(1):69-76. doi: 10.1080/10520295.2022.2147218. Epub 2022 Nov 29. PMID: 36444536. 11: Neopane D, Kushwaha P. Carvacrol in asthma management: a comprehensive review of its therapeutic potential and mechanisms of action. Pharmacol Rep. 2025 Jun;77(3):610-623. doi: 10.1007/s43440-025-00709-6. Epub 2025 Mar 11. PMID: 40067636. 12: Mbese Z, Aderibigbe BA. Biological Efficacy of Carvacrol Analogues. Recent Pat Antiinfect Drug Discov. 2018;13(3):207-216. doi: 10.2174/1574891X14666181205111821. PMID: 30516115. 13: Morais ANP, Lima LF, Silva AFB, Lienou LL, Ferreira ACA, Watanabe YF, Joaquim DC, Alves BG, Pereira AF, Alves DR, Oliveira AC, Morais SM, Magalhães- Padilha DM, Figueiredo JR, Gastal EL. Effect of carvacrol antioxidant capacity on oocyte maturation and embryo production in cattle. Zygote. 2023 Apr;31(2):173-179. doi: 10.1017/S0967199422000673. Epub 2023 Feb 20. PMID: 36804925. 14: Costa MF, Durço AO, Rabelo TK, Barreto RSS, Guimarães AG. Effects of Carvacrol, Thymol and essential oils containing such monoterpenes on wound healing: a systematic review. J Pharm Pharmacol. 2019 Feb;71(2):141-155. doi: 10.1111/jphp.13054. Epub 2018 Dec 7. PMID: 30537169. 15: Suntres ZE, Coccimiglio J, Alipour M. The bioactivity and toxicological actions of carvacrol. Crit Rev Food Sci Nutr. 2015;55(3):304-18. doi: 10.1080/10408398.2011.653458. PMID: 24915411. 16: de Carvalho FO, Silva ÉR, Gomes IA, Santana HSR, do Nascimento Santos D, de Oliveira Souza GP, de Jesus Silva D, Monteiro JCM, de Albuquerque Júnior RLC, de Souza Araújo AA, Nunes PS. Anti-inflammatory and antioxidant activity of carvacrol in the respiratory system: A systematic review and meta-analysis. Phytother Res. 2020 Sep;34(9):2214-2229. doi: 10.1002/ptr.6688. Epub 2020 Apr 6. PMID: 32249518. 17: Yan C, Kuang W, Jin L, Wang R, Niu L, Xie C, Ding J, Liao Y, Wang L, Wan H, Ma G. Carvacrol protects mice against LPS-induced sepsis and attenuates inflammatory response in macrophages by modulating the ERK1/2 pathway. Sci Rep. 2023 Aug 7;13(1):12809. doi: 10.1038/s41598-023-39665-7. PMID: 37550359; PMCID: PMC10406886. 18: Zhao W, Deng C, Han Q, Xu H, Chen Y. Carvacrol may alleviate vascular inflammation in diabetic db/db mice. Int J Mol Med. 2020 Sep;46(3):977-988. doi: 10.3892/ijmm.2020.4654. Epub 2020 Jun 19. Erratum in: Int J Mol Med. 2023 Oct;52(4):90. doi: 10.3892/ijmm.2023.5293. PMID: 32583003; PMCID: PMC7388828. 19: Niu C, Wang C, Yang Y, Chen R, Zhang J, Chen H, Zhuge Y, Li J, Cheng J, Xu K, Chu M, Ren C, Zhang C, Jia C. Carvacrol Induces Candida albicans Apoptosis Associated With Ca2+/Calcineurin Pathway. Front Cell Infect Microbiol. 2020 Apr 30;10:192. doi: 10.3389/fcimb.2020.00192. PMID: 32426298; PMCID: PMC7203418. 20: Fermiano TH, Perez de Souza JV, Murase LS, Salvaterra Pasquini JP, de Lima Scodro RB, Zanetti Campanerut-Sá PA, Caleffi-Ferracioli KR, Dias Siqueira VL, Meneguello JE, Vieira Teixeira JJ, Cardoso RF. Antimicrobial activity of carvacrol and its derivatives on Mycobacterium spp.: systematic review of preclinical studies. Future Med Chem. 2024 Apr;16(7):679-688. doi: 10.4155/fmc-2023-0249. Epub 2024 Feb 23. PMID: 38390753.