PF-07853578 | PNPLA3 degrader | CAS#3036158-98-9

MedKoo Cat#: 128935 | Name: PF-07853578

Description:

WARNING: This product is for research use only, not for human or veterinary use.

PF-07853578 is a PNPLA3 degrader with an EC50 of 8 nM.

Chemical Structure

PF-07853578

CAS#3036158-98-9

Theoretical Analysis

MedKoo Cat#: 128935

Name: PF-07853578

CAS#: 3036158-98-9

Chemical Formula: C16H19ClF2N2O4S

Exact Mass: 408.0722

Molecular Weight: 408.84

Elemental Analysis: C, 47.00; H, 4.68; Cl, 8.67; F, 9.29; N, 6.85; O, 15.65; S, 7.84

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

PF-07853578; PF 07853578; PF07853578

IUPAC/Chemical Name

4-chlorophenyl (R)-3,3-difluoro-5-((R)-5-methyl-1,1-dioxidoisothiazolidin-2-yl)piperidine-1-carboxylate

InChi Key

LWZQGRRGKYWBQG-DGCLKSJQSA-N

InChi Code

InChI=1S/C16H19ClF2N2O4S/c1-11-6-7-21(26(11,23)24)13-8-16(18,19)10-20(9-13)15(22)25-14-4-2-12(17)3-5-14/h2-5,11,13H,6-10H2,1H3/t11-,13-/m1/s1

SMILES Code

O=S1(N(CC[C@H]1C)[C@H]2CN(CC(F)(C2)F)C(OC3=CC=C(C=C3)Cl)=O)=O

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 408.84 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.