MedKoo Cat#: 128931 | Name: SJPYT-310
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

SJPYT-310 is a potent and selective PXR antagonist (IC50 values are 4 and 9 nM for binding and cellular activity, respectively).

Chemical Structure

SJPYT-310
SJPYT-310
CAS#2883814-84-2

Theoretical Analysis

MedKoo Cat#: 128931

Name: SJPYT-310

CAS#: 2883814-84-2

Chemical Formula: C27H36N4O3

Exact Mass: 464.2787

Molecular Weight: 464.61

Elemental Analysis: C, 69.80; H, 7.81; N, 12.06; O, 10.33

Price and Availability

Size Price Availability Quantity
10mg USD 450.00 2 Weeks
50mg USD 1,050.00 2 Weeks
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Related CAS #
No Data
Synonym
SJPYT 310; SJPYT-310; SJPYT310
IUPAC/Chemical Name
(S)-N-(5-(tert-butyl)-2-(pentan-2-yloxy)phenyl)-1-(2-methoxy-5-methylphenyl)-5-methyl-1H-1,2,3-triazole-4-carboxamide
InChi Key
UOXKTTLWMUQDFC-SFHVURJKSA-N
InChi Code
InChI=1S/C27H36N4O3/c1-9-10-18(3)34-23-14-12-20(27(5,6)7)16-21(23)28-26(32)25-19(4)31(30-29-25)22-15-17(2)11-13-24(22)33-8/h11-16,18H,9-10H2,1-8H3,(H,28,32)/t18-/m0/s1
SMILES Code
CC1=C(C(NC2=C(C=CC(C(C)(C)C)=C2)O[C@@H](C)CCC)=O)N=NN1C3=C(C=CC(C)=C3)OC
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 464.61 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Garcia-Maldonado E, Huber AD, Chai SC, Nithianantham S, Li Y, Wu J, Poudel S, Miller DJ, Seetharaman J, Chen T. Chemical manipulation of an activation/inhibition switch in the nuclear receptor PXR. Nat Commun. 2024 May 14;15(1):4054. doi: 10.1038/s41467-024-48472-1. PMID: 38744881; PMCID: PMC11094003.