MedKoo Cat#: 128914 | Name: DMTr-TNA A(Bz)-amidite
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

DMTr-TNA A(Bz)-amidite is a nucleoside building block that has been used in the synthesis of oligonucleotides for the study of prebiotic RNA evolution.

Chemical Structure

DMTr-TNA A(Bz)-amidite
DMTr-TNA A(Bz)-amidite
CAS#325683-93-0

Theoretical Analysis

MedKoo Cat#: 128914

Name: DMTr-TNA A(Bz)-amidite

CAS#: 325683-93-0

Chemical Formula: C46H50N7O7P

Exact Mass: 843.3509

Molecular Weight: 843.92

Elemental Analysis: C, 65.47; H, 5.97; N, 11.62; O, 13.27; P, 3.67

Price and Availability

Size Price Availability Quantity
1mg USD 350.00 2 Weeks
5mg USD 750.00 2 Weeks
10mg USD 1,150.00 2 Weeks
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Related CAS #
No Data
Synonym
DMTr-TNA A(Bz)-amidite;
IUPAC/Chemical Name
(2R,3R,4S)-2-(6-benzamido-9H-purin-9-yl)-4-(bis(4-methoxyphenyl)(phenyl)methoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChi Key
QDGHMYBPKHSPSZ-BZWOVQDPSA-N
InChi Code
InChI=1S/C46H50N7O7P/c1-31(2)53(32(3)4)61(58-27-13-26-47)60-41-39(28-57-45(41)52-30-50-40-42(48-29-49-43(40)52)51-44(54)33-14-9-7-10-15-33)59-46(34-16-11-8-12-17-34,35-18-22-37(55-5)23-19-35)36-20-24-38(56-6)25-21-36/h7-12,14-25,29-32,39,41,45H,13,27-28H2,1-6H3,(H,48,49,51,54)/t39-,41+,45+,61?/m0/s1
SMILES Code
COC(C=C1)=CC=C1C(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)O[C@H]4CO[C@@H](N5C=NC6=C(NC(C7=CC=CC=C7)=O)N=CN=C65)[C@@H]4OP(N(C(C)C)C(C)C)OCCC#N
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 843.92 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Yang, Y.-W., Zhang, S., McCullum, E.O., et al. Experimental evidence that GNA and TNA were not sequential polymers in the prebiotic evolution of RNA. J. Mol. Evol. 65(3), 289-295 (2007).