AMX5160 is a Reversible, Noncovalent Bruton’s Tyrosine Kinase Inhibitor Targeting BTK C481S Mutation. AMX5160 showed in vivo efficacy and induced tumor suppression (TGI up to 82%) in mutant BTKC481S mouse xenograftmodels.
MedKoo Cat#: 128909
Name: AMX5160
CAS#: N/A
Chemical Formula: C28H27ClN4O3
Exact Mass: 502.1772
Molecular Weight: 503.00
Elemental Analysis: C, 66.86; H, 5.41; Cl, 7.05; N, 11.14; O, 9.54
The following data is based on the product molecular weight 503.00 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
