HMRZ-62 is a potent, selective inverse agonist of the human histamine H3 receptor. It works by blocking H3 autoreceptors in the brain, which increases the release of histamine and other neurotransmitters like acetylcholine, dopamine, and norepinephrine. This mechanism enhances wakefulness, cognition, and attention, making HMRZ-62 a candidate for treating sleep disorders, cognitive impairments, and neurodegenerative diseases.
MedKoo Cat#: 146340
Name: HMRZ-62
CAS#: 287118-33-6
Chemical Formula: C21H14ClN5O6S5
Exact Mass: 626.9236
Molecular Weight: 628.12
Elemental Analysis: C, 40.16; H, 2.25; Cl, 5.64; N, 11.15; O, 15.28; S, 25.52
The following data is based on the product molecular weight 628.12 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
