SRI-31255 is a Potent, Selective, and Orally Bioavailable LRRK2 Inhibitor. SRI-31255, exhibits excellentLRRK2 inhibition activity and, high selectivity across the kinome. Further, the molecule has acceptable absorption, distribution, metabolism, and excretion (ADME), and pharmacokinetic (PK)properties, as well as brain permeability and no off-target liabilities.
MedKoo Cat#: 128908
Name: SRI-31255
CAS#: N/A
Chemical Formula: C15H14N4
Exact Mass: 250.1218
Molecular Weight: 250.31
Elemental Analysis: C, 71.98; H, 5.64; N, 22.38
The following data is based on the product molecular weight 250.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
