Rheoemodin | CAS#52940-12-2 | biochemical

MedKoo Cat#: 146329 | Name: Rheoemodin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Rheoemodin is an anthraquinone derivative found in certain medicinal plants, such as Rheum species (rhubarb), and is structurally related to emodin. It exhibits various biological activities, including anti-inflammatory, antimicrobial, and anticancer effects, though its applications are primarily in pharmacological research. Its mechanism of action involves modulation of signaling pathways like NF-κB and MAPK, as well as inhibition of certain enzymes involved in inflammation and cell proliferation.

Chemical Structure

Rheoemodin

CAS#52940-12-2

Theoretical Analysis

MedKoo Cat#: 146329

Name: Rheoemodin

CAS#: 52940-12-2

Chemical Formula: C14H8O6

Exact Mass: 272.0321

Molecular Weight: 272.21

Elemental Analysis: C, 61.77; H, 2.96; O, 35.26

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Rheoemodin;

IUPAC/Chemical Name

1,3,6,8-tetrahydroxyanthracene-9,10-dione

InChi Key

NTGIIKCGBNGQAR-UHFFFAOYSA-N

InChi Code

1S/C14H8O6/c15-5-1-7-11(9(17)3-5)14(20)12-8(13(7)19)2-6(16)4-10(12)18/h1-4,15-18H

SMILES Code

OC1=CC2=C(C(O)=C1)C(=O)C3=C(O)C=C(O)C=C3C2=O

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 272.21 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Wang M, Kornsakulkarn J, Srichomthong K, Feng T, Liu JK, Isaka M, Thongpanchang C. Antimicrobial anthraquinones from cultures of the ant pathogenic fungus Cordyceps morakotii BCC 56811. J Antibiot (Tokyo). 2019 Mar;72(3):141-147. doi: 10.1038/s41429-018-0135-y. Epub 2019 Jan 9. PMID: 30622295. 2: Kang MJ, Wu T, Wijeratne EM, Lau EC, Mason DJ, Mesa C, Tillotson J, Zhang DD, Gunatilaka AA, La Clair JJ, Chapman E. Functional chromatography reveals three natural products that target the same protein with distinct mechanisms of action. Chembiochem. 2014 Sep 22;15(14):2125-31. doi: 10.1002/cbic.201402258. Epub 2014 Aug 14. PMID: 25125376; PMCID: PMC4187115. 3: Noinart J, Buttachon S, Dethoup T, Gales L, Pereira JA, Urbatzka R, Freitas S, Lee M, Silva AMS, Pinto MMM, Vasconcelos V, Kijjoa A. A New Ergosterol Analog, a New Bis-Anthraquinone and Anti-Obesity Activity of Anthraquinones from the Marine Sponge-Associated Fungus Talaromyces stipitatus KUFA 0207. Mar Drugs. 2017 May 16;15(5):139. doi: 10.3390/md15050139. PMID: 28509846; PMCID: PMC5450545.