MedKoo Cat#: 128873 | Name: Isosorbide-2-nitrate
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Isosorbide-2-nitrate is a nitric oxide (NO) donor and an active metabolite of isosorbide dinitrate.

Chemical Structure

Isosorbide-2-nitrate
Isosorbide-2-nitrate
CAS#16106-20-0

Theoretical Analysis

MedKoo Cat#: 128873

Name: Isosorbide-2-nitrate

CAS#: 16106-20-0

Chemical Formula: C6H9NO6

Exact Mass: 191.0430

Molecular Weight: 191.14

Elemental Analysis: C, 37.70; H, 4.75; N, 7.33; O, 50.22

Price and Availability

Size Price Availability Quantity
1mg USD 350.00 2 Weeks
5mg USD 650.00 2 Weeks
10mg USD 950.00 2 Weeks
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Related CAS #
No Data
Synonym
Isosorbide-2-nitrate; IS 2-MN; Isosorbide 2-mononitrate
IUPAC/Chemical Name
(3S,3aS,6R,6aR)-6-hydroxyhexahydrofuro[3,2-b]furan-3-yl nitrate
InChi Key
YWXYYJSYQOXTPL-JGWLITMVSA-N
InChi Code
InChI=1S/C6H9NO6/c8-3-1-11-6-4(13-7(9)10)2-12-5(3)6/h3-6,8H,1-2H2/t3-,4+,5-,6-/m1/s1
SMILES Code
O[C@H](CO1)[C@]2([H])[C@@]1([H])[C@@H](O[N+]([O-])=O)CO2
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 191.14 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Raddino, R., Caretta, G., Bonadei, I., et al. Differences between nitrates: Role of isosorbide 2-mononitrate. J. Cardiovasc. Med. (Hagerstown) 11(7), 486-492 (2010). 2. Patel, B.D., Pulakundam, N., Gadekar, A.R., et al. Development and validation of a chiral LC-ESI-MS/MS method for simultaneous determination of the enantiomeric metabolites isosorbide 2-mononitrate and isosorbide 5-mononitrate of isosorbide dinitrate in rat and human plasma. J. Pharm. Biomed. Anal. 174, 396-405 (2019).