Phoratoxon is the active and toxic metabolite of the organophosphorus insecticide phorate, formed through oxidative metabolism in organisms and the environment. It functions as a potent acetylcholinesterase (AChE) inhibitor, leading to the accumulation of acetylcholine at nerve synapses and causing continuous nerve stimulation. This results in symptoms such as muscle twitching, respiratory distress, and potentially death in insects and non-target species, including humans. Due to its high toxicity, phoratoxon is primarily of toxicological concern rather than direct application use.
MedKoo Cat#: 146307
Name: Phoratoxon
CAS#: 2600-69-3
Chemical Formula: C7H17O3PS2
Exact Mass: 244.0357
Molecular Weight: 244.30
Elemental Analysis: C, 34.41; H, 7.01; O, 19.65; P, 12.68; S, 26.25
The following data is based on the product molecular weight 244.30 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
