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MedKoo Cat#: 146302 | Name: Ferimzone

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Ferimzone is a systemic fungicide used primarily in agriculture to control fungal diseases such as rice blast caused by Magnaporthe oryzae. It belongs to the pyrimidine class of fungicides and works by inhibiting fungal respiration, specifically targeting the cytochrome bc1 complex in the mitochondrial electron transport chain. This disruption impairs energy production in fungal cells, leading to growth inhibition and death. Ferimzone is valued for its effectiveness in rice cultivation and its role in resistance management when used in rotation with other fungicides.

Chemical Structure

Ferimzone
Ferimzone
CAS#89269-64-7

Theoretical Analysis

MedKoo Cat#: 146302

Name: Ferimzone

CAS#: 89269-64-7

Chemical Formula: C15H18N4

Exact Mass: 254.1531

Molecular Weight: 254.34

Elemental Analysis: C, 70.84; H, 7.13; N, 22.03

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Ferimzone; Meferimzone;
IUPAC/Chemical Name
(Z)-4,6-dimethyl-2-(2-(1-(o-tolyl)ethylidene)hydrazinyl)pyrimidine
InChi Key
GOWLARCWZRESHU-AQTBWJFISA-N
InChi Code
1S/C15H18N4/c1-10-7-5-6-8-14(10)13(4)18-19-15-16-11(2)9-12(3)17-15/h5-9H,1-4H3,(H,16,17,19)/b18-13-
SMILES Code
C\C(=N\NC1=NC(C)=CC(C)=N1)C2=C(C)C=CC=C2
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 254.34 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Food Safety Commission of Japan. Ferimzone (Third Edition) (Pesticides). Food Saf (Tokyo). 2025 Mar 21;13(1):15-18. doi: 10.14252/foodsafetyfscj.D-25-00007. PMID: 40151325; PMCID: PMC11937839. 2: Zhang Y, Li J, Liu X, Gao W, Song S, Rong Y, Tan L, Glukhareva TV, Bakulev VA, Fan Z. Exploration of Fungicidal Activity and Mode of Action of Ferimzone Analogs. J Agric Food Chem. 2023 Mar 1;71(8):3705-3718. doi: 10.1021/acs.jafc.2c08504. Epub 2023 Feb 10. PMID: 36763904. 3: Harata K, Daimon H, Okuno T. Trade-Off Relation between Fungicide Sensitivity and Melanin Biosynthesis in Plant Pathogenic Fungi. iScience. 2020 Oct 8;23(11):101660. doi: 10.1016/j.isci.2020.101660. PMID: 33117970; PMCID: PMC7582099. 4: Kim SH, Baek JW, Eun HR, Lee YJ, Kim SM, Jeong MJ, Lee YH, Noh HH, Shin Y. Optimization of Ferimzone and Tricyclazole Analysis in Rice Straw Using QuEChERS Method and Its Application in UAV-Sprayed Residue Study. Foods. 2024 Nov 4;13(21):3517. doi: 10.3390/foods13213517. PMID: 39517301; PMCID: PMC11545821. 5: Yuan X, Kim CJ, Jeong WT, Kyung KS, Noh HH. Factors Affecting Incurred Pesticide Extraction in Cereals. Molecules. 2023 Jul 31;28(15):5774. doi: 10.3390/molecules28155774. PMID: 37570743; PMCID: PMC10420941. 6: Kimura N, Fukuchi A. Management of melanin biosynthesis dehydratase inhibitor (MBI-D)-resistance in Pyricularia oryzae using a non-MBI-D fungicidal application program for nursery boxes and a diclocymet and ferimzone mixture for field foliar applications. J Pestic Sci. 2018 Nov 20;43(4):287-292. doi: 10.1584/jpestics.D18-023. Erratum in: J Pestic Sci. 2019 Feb 20;44(1):87. doi: 10.1584/jpestics.C19-01. PMID: 30479552; PMCID: PMC6240774. 7: Cho HR, Park JS, Kim J, Han SB, Choi YS. Multiresidue method for the quantitation of 20 pesticides in aquatic products. Anal Bioanal Chem. 2015 Dec;407(30):9043-52. doi: 10.1007/s00216-015-9071-x. Epub 2015 Oct 14. PMID: 26466578. 8: Nagai T. Sensitivity differences among five species of aquatic fungi and fungus-like organisms for seven fungicides with various modes of action. J Pestic Sci. 2020 Nov 20;45(4):223-229. doi: 10.1584/jpestics.D20-035. PMID: 33304191; PMCID: PMC7691557. 9: Li M, Long Y, Shao L, Meng J, Zheng Z, Wu Y, Zhou X, Liu L, Li Z, Wu Z, Yang S. Targeting tubulin protein to combat fungal disease: Design, synthesis, and its new mechanistic insights of benzimidazole hydrazone derivatives. Int J Biol Macromol. 2025 Apr;300:140226. doi: 10.1016/j.ijbiomac.2025.140226. Epub 2025 Jan 22. PMID: 39855516. 10: Eun HR, Kim SH, Lee YH, Kim SM, Lee YJ, Jung HY, Min YG, Noh HH, Shin Y. Comparison of off-target pesticide drift in paddy fields from unmanned aerial vehicle spraying using cellulose deposition sampler. Ecotoxicol Environ Saf. 2024 Oct 15;285:117075. doi: 10.1016/j.ecoenv.2024.117075. Epub 2024 Sep 20. PMID: 39305778. 11: Baek JW, Eun HR, Kim SH, Lee YH, Jeong MJ, Han X, Min YG, Noh HH, Shin Y. Reduction of pesticide dosage and off-target drift with enhanced control efficacy in unmanned aerial vehicle-based application using lecithin adjuvants. Pest Manag Sci. 2024 Nov 18. doi: 10.1002/ps.8551. Epub ahead of print. PMID: 39556405. 12: Otake T, Aoyagi Y, Yarita T. Multiresidue analysis and monitoring of pesticides in rice by pressurized liquid extraction. J Environ Sci Health B. 2009 Jun;44(5):423-7. doi: 10.1080/10934520902719704. PMID: 20183045.

View History

CB-03-05

CB-03-05