NF272 | P2YR inhibitor

MedKoo Cat#: 128831 | Name: NF272

Description:

WARNING: This product is for research use only, not for human or veterinary use.

NF272 is a P2YR inhibitor.

Chemical Structure

NF272

CAS#N/A

Theoretical Analysis

MedKoo Cat#: 128831

Name: NF272

CAS#: N/A

Chemical Formula: C32H25N3O13S3

Exact Mass: 755.0549

Molecular Weight: 755.74

Elemental Analysis: C, 50.86; H, 3.33; N, 5.56; O, 27.52; S, 12.73

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

NF272; NF-272; NF 272

IUPAC/Chemical Name

8-(4-methyl-3-(3-((phenoxycarbonyl)amino)benzamido)benzamido)naphthalene-1,3,5-trisulfonic acid

InChi Key

UMFKTDZRJFGQEB-UHFFFAOYSA-N

InChi Code

InChI=1S/C32H25N3O13S3/c1-18-10-11-20(15-26(18)35-30(36)19-6-5-7-21(14-19)33-32(38)48-22-8-3-2-4-9-22)31(37)34-25-12-13-27(50(42,43)44)24-16-23(49(39,40)41)17-28(29(24)25)51(45,46)47/h2-17H,1H3,(H,33,38)(H,34,37)(H,35,36)(H,39,40,41)(H,42,43,44)(H,45,46,47)

SMILES Code

O=C(C1=CC=C(C)C(NC(C2=CC=CC(NC(OC3=CC=CC=C3)=O)=C2)=O)=C1)NC4=C(C(S(=O)(O)=O)=CC(S(=O)(O)=O)=C5)C5=C(S(=O)(O)=O)C=C4

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 755.74 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Brockmann N, Sureechatchaiyan P, Müller D, Hennicke T, Hausmann R, Fritz G, Hamacher A, Kassack MU. Profiling of a suramin-derived compound library at recombinant human P2Y receptors identifies NF272 as a competitive but non-selective P2Y2 receptor antagonist. Purinergic Signal. 2019 Sep;15(3):287-298. doi: 10.1007/s11302-019-09663-4. Epub 2019 Jul 3. PMID: 31270713; PMCID: PMC6737154.