MedKoo Cat#: 146264 | Name: Heterophos

Description:

WARNING: This product is for research use only, not for human or veterinary use.

​Heterophos, with the chemical name O-ethyl O-phenyl S-propyl phosphorothioate and CAS number 40626-35-5, is an organophosphorus pesticide used as both an insecticide and nematicide. It is commonly applied in agricultural settings to control a variety of pests, including insects and nematodes, that affect crops such as rice and vegetables.​ The mechanism of action of Heterophos involves the inhibition of acetylcholinesterase (AChE), an enzyme critical for the proper functioning of the nervous system in insects and nematodes. By binding to AChE, Heterophos prevents the breakdown of acetylcholine, leading to the accumulation of this neurotransmitter at synaptic junctions. This accumulation results in continuous nerve stimulation, paralysis, and ultimately the death of the target pests.

Chemical Structure

Heterophos
Heterophos
CAS#40626-35-5

Theoretical Analysis

MedKoo Cat#: 146264

Name: Heterophos

CAS#: 40626-35-5

Chemical Formula: C11H17O3PS

Exact Mass: 260.0636

Molecular Weight: 260.29

Elemental Analysis: C, 50.76; H, 6.58; O, 18.44; P, 11.90; S, 12.32

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Heterophos;
IUPAC/Chemical Name
O-ethyl O-phenyl S-propyl phosphorothioate
InChi Key
XRAFOYUFLGWMQB-UHFFFAOYSA-N
InChi Code
1S/C11H17O3PS/c1-3-10-16-15(12,13-4-2)14-11-8-6-5-7-9-11/h5-9H,3-4,10H2,1-2H3
SMILES Code
CCCSP(=O)(OCC)OC1=CC=CC=C1
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 260.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Spynu EI, Sova RE, Stroĭ AN, Ivashina SA, Fedorishchak TA. Obosnovanie gigienicheskogo normativa soderzhaniia geterofosa v pochve [Basis for the hygienic standards for the concentration of heterophos in soil]. Gig Sanit. 1986 Mar;(3):75-6. Russian. PMID: 3699469. 2: Ivashina SA. Gigienicheskaia otsenka zagriazneniia pochvy geterofosom [Hygienic estimation of soil contamination by heterophos]. Gig Sanit. 1984 Nov;(11):76-7. Russian. PMID: 6526297. 3: Ershov E, Shlosberg A, Hanji V, Kagan J. The role of microsomal mixed function oxidases in the metabolism and mechanism of action of certain organophosphorus insecticides. Drug Metabol Drug Interact. 1994;11(2):139-52. doi: 10.1515/dmdi.1994.11.2.139. PMID: 12369597. 4: Komissarova LA. Izuchenie mutagennoĭ aktivnosti novykh fosfororganicheskikh pestitsidov [Mutagenic activity of new organophosphorus pesticides]. Gig Sanit. 1986 Jan;(1):65-6. Russian. PMID: 3949219. 5: Gantverg AN. Opredelenie fenolov i nekotorykh pestitsidov v rybe kolorimetricheskim metodom [Determining the levels of phenols and various pesticides in fish by the colorimetric method]. Gig Sanit. 1988 Sep;(9):36-7. Russian. PMID: 3234801. 6: Drobiazko VP, Manenko AK. Opredelenie iskhodnykh veshchestv sinteza geterofosa i étafosa v vode vodoemov [Determination of the parent substances of heterofos and etafos synthesis in reservoir water]. Gig Sanit. 1986 Jun;(6):61-2. Russian. PMID: 3744072. 7: Chura DA, Kirik LV, Pavliuk IaD, Manenko AK. Nauchnoe obosnovanie predel'no dopustimoĭ kontsentratsii O-etil-O-fenil khlortiofosfata v vode vodoemov [Scientific substantiation of the maximum permissible level of O-ethyl-O- phenylchlorthiophosphate in reservoir water]. Gig Sanit. 1988 Sep;(9):67-9. Russian. PMID: 3234811. 8: Trinus FP, Braver-Chernobul'skaia BS, Luĭk AI, Boldeskul AE, Velichko AN. Izmeneniia vtorichnoĭ i tretichnoĭ struktury syvorotochnogo al'bumina pri vzaimodeĭstvii s ligandami razlichnogo stroeniia [Changes in the secondary and tertiary structure of serum albumin in interactions with ligands of various structures]. Vopr Med Khim. 1984 Jul-Aug;30(4):48-50. Russian. PMID: 6239449.