Diclomezine is a fungicide belonging to the pyridazinone class, chemically known as 6-(3,5-dichloro-4-methylphenyl)pyridazin-3(2H)-one. It is primarily used to control fungal diseases in crops such as rice, particularly targeting sheath blight caused by Rhizoctonia solani. The compound acts by inhibiting enzymes involved in chitin and glucan synthesis, disrupting the formation of the fungal cell wall, leading to cell lysis and death . Diclomezine is applied as a seed treatment or foliar spray and is available in various formulations, including soluble concentrates and wettable powders . It is moderately toxic to honeybees but shows relative non-toxicity towards most aquatic organisms and birds .
MedKoo Cat#: 146238
Name: Diclomezine
CAS#: 62865-36-5
Chemical Formula: C11H8Cl2N2O
Exact Mass: 254.0014
Molecular Weight: 255.10
Elemental Analysis: C, 51.79; H, 3.16; Cl, 27.79; N, 10.98; O, 6.27
The following data is based on the product molecular weight 255.10 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
