MedKoo Cat#: 146228 | Name: Diofenolan

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Diofenolan is a synthetic organophosphorus compound primarily studied for its potential applications as a pesticide or growth regulator in agricultural settings. It has shown activity in disrupting endocrine function in insects, interfering with hormonal pathways that regulate development and reproduction. The mechanism of action involves mimicking or blocking natural hormones, particularly by binding to hormone receptors and altering gene expression related to growth and metamorphosis. Due to its endocrine-disrupting potential, diofenolan is also studied for its environmental impact and safety in pest control applications.

Chemical Structure

Diofenolan
Diofenolan
CAS#63837-33-2

Theoretical Analysis

MedKoo Cat#: 146228

Name: Diofenolan

CAS#: 63837-33-2

Chemical Formula: C18H20O4

Exact Mass: 300.1362

Molecular Weight: 300.35

Elemental Analysis: C, 71.98; H, 6.71; O, 21.31

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Diofenolan;
IUPAC/Chemical Name
2-ethyl-4-((4-phenoxyphenoxy)methyl)-1,3-dioxolane
InChi Key
ZDOOQPFIGYHZFV-UHFFFAOYSA-N
InChi Code
1S/C18H20O4/c1-2-18-20-13-17(22-18)12-19-14-8-10-16(11-9-14)21-15-6-4-3-5-7-15/h3-11,17-18H,2,12-13H2,1H3
SMILES Code
CCC1OCC(COC2=CC=C(OC3=CC=CC=C3)C=C2)O1
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 300.35 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Abe R, Toyota K, Miyakawa H, Watanabe H, Oka T, Miyagawa S, Nishide H, Uchiyama I, Tollefsen KE, Iguchi T, Tatarazako N. Diofenolan induces male offspring production through binding to the juvenile hormone receptor in Daphnia magna. Aquat Toxicol. 2015 Feb;159:44-51. doi: 10.1016/j.aquatox.2014.11.015. Epub 2014 Nov 24. PMID: 25506888. 2: Singh S, Kumar K. Effect of juvenoids pyriproxyfen and diofenolan on embryogenesis and postembryonic development of blow fly Chrysomya megacephala (Diptera: Calliphoridae) following egg treatment. Parasitol Res. 2015 Sep;114(9):3213-22. doi: 10.1007/s00436-015-4536-6. Epub 2015 May 24. PMID: 26003811. 3: Ghoneim KS, Bream AS, Tanani MA, Nassar MM. Effectiveness of IGRS (CGA-184699) and (CGA-259205) on the respiratory metabolism of the red palm weevil, Rhynchophorus ferrugineus (Coleoptera: Curculionidae). Meded Rijksuniv Gent Fak Landbouwkd Toegep Biol Wet. 2001;66(2a):413-23. PMID: 12425062.