MedKoo Cat#: 146184 | Name: Maritimein

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Maritimein is a flavonoid compound belonging to the aurone subclass, found in plants such as Coreopsis maritima. It exhibits antioxidant, anti-inflammatory, and potential antimicrobial activities. Maritimein's mechanism of action involves scavenging free radicals and modulating inflammatory signaling pathways, such as NF-κB, which helps reduce oxidative stress and inflammation. Due to these properties, it is being investigated for use in skincare, anti-aging products, and as a natural therapeutic agent for inflammatory-related diseases.

Chemical Structure

Maritimein
Maritimein
CAS#490-54-0

Theoretical Analysis

MedKoo Cat#: 146184

Name: Maritimein

CAS#: 490-54-0

Chemical Formula: C21H20O11

Exact Mass: 448.1006

Molecular Weight: 448.38

Elemental Analysis: C, 56.25; H, 4.50; O, 39.25

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Maritimein;
IUPAC/Chemical Name
2-((Z)-3,4-dihydroxybenzylidene)-7-hydroxy-6-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)benzofuran-3(2H)-one
InChi Key
SYRURBPRFQUYQS-RHEJLWEFSA-N
InChi Code
1S/C21H20O11/c22-7-14-16(26)18(28)19(29)21(32-14)31-12-4-2-9-15(25)13(30-20(9)17(12)27)6-8-1-3-10(23)11(24)5-8/h1-6,14,16,18-19,21-24,26-29H,7H2/b13-6-/t14-,16-,18+,19-,21-/m1/s1
SMILES Code
OC[C@H]1O[C@@H](OC2=CC=C3C(=O)\C(OC3=C2O)=C\C4=CC=C(O)C(O)=C4)[C@H](O)[C@@H](O)[C@@H]1O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 448.38 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Henrique Santana Silveira P, Pita SSDR. Druggable sites identification in Streptococcus mutans VicRK system evaluated by catechols. J Biomol Struct Dyn. 2023;41(21):12000-12015. doi: 10.1080/07391102.2023.2166118. Epub 2023 Jan 26. PMID: 36703608. 2: Lim A, Kumara NT, Tan AL, Mirza AH, Chandrakanthi RL, Petra MI, Ming LC, Senadeera GK, Ekanayake P. Potential natural sensitizers extracted from the skin of Canarium odontophyllum fruits for dye-sensitized solar cells. Spectrochim Acta A Mol Biomol Spectrosc. 2015 Mar 5;138:596-602. doi: 10.1016/j.saa.2014.11.102. Epub 2014 Dec 11. PMID: 25541396. 3: Chen LX, Hu DJ, Lam SC, Ge L, Wu D, Zhao J, Long ZR, Yang WJ, Fan B, Li SP. Comparison of antioxidant activities of different parts from snow chrysanthemum (Coreopsis tinctoria Nutt.) and identification of their natural antioxidants using high performance liquid chromatography coupled with diode array detection and mass spectrometry and 2,2'-azinobis(3-ethylbenzthiazoline-sulfonic acid)diammonium salt-based assay. J Chromatogr A. 2016 Jan 8;1428:134-42. doi: 10.1016/j.chroma.2015.10.037. Epub 2015 Oct 19. PMID: 26521095. 4: Hinou J, Harvala C, Philianos S. Substances polyphénoliques des feuilles de Cynara scolymus L [Polyphenolic substances of Cynara scolymus L. leaves]. Ann Pharm Fr. 1989;47(2):95-8. French. PMID: 2610472. 5: Du D, Yao L, Zhang R, Shi N, Shen Y, Yang X, Zhang X, Jin T, Liu T, Hu L, Xing Z, Criddle DN, Xia Q, Huang W, Sutton R. Protective effects of flavonoids from Coreopsis tinctoria Nutt. on experimental acute pancreatitis via Nrf-2/ARE- mediated antioxidant pathways. J Ethnopharmacol. 2018 Oct 5;224:261-272. doi: 10.1016/j.jep.2018.06.003. Epub 2018 Jun 2. PMID: 29870787.