MedKoo Cat#: 146166 | Name: Menthiafolin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Menthiafolin is a derivative of folic acid, commonly used in pharmaceutical and nutritional applications to support brain health and cognitive function. It acts as a bioactive form of folate, providing essential nutrients for cellular processes, particularly in the central nervous system. Menthiafolin works by enhancing the activity of enzymes involved in folate metabolism, promoting the synthesis of neurotransmitters and reducing the risk of neurological deficiencies. It is often used to improve mood, memory, and overall brain function, especially in individuals with folate-related deficiencies.

Chemical Structure

Menthiafolin
Menthiafolin
CAS#19351-64-5

Theoretical Analysis

MedKoo Cat#: 146166

Name: Menthiafolin

CAS#: 19351-64-5

Chemical Formula: C26H36O12

Exact Mass: 540.2207

Molecular Weight: 540.56

Elemental Analysis: C, 57.77; H, 6.71; O, 35.52

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Menthiafolin;
IUPAC/Chemical Name
(4aS,5R)-1-oxo-6-(((2R,3S,4R,5R,6S)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-5-vinyl-4,4a,5,6-tetrahydro-1H,3H-pyrano[3,4-c]pyran-3-yl (E)-6-hydroxy-2,6-dimethylocta-2,7-dienoate
InChi Key
FPDCQAOWJZHIQX-RQHRMXDNSA-N
InChi Code
1S/C26H36O12/c1-5-14-15-10-18(36-22(31)13(3)8-7-9-26(4,33)6-2)37-23(32)16(15)12-34-24(14)38-25-21(30)20(29)19(28)17(11-27)35-25/h5-6,8,12,14-15,17-21,24-25,27-30,33H,1-2,7,9-11H2,3-4H3/b13-8+/t14-,15+,17+,18?,19+,20-,21+,24?,25-,26?/m1/s1
SMILES Code
C\C(=C/CCC(C)(O)C=C)C(=O)OC1C[C@H]2[C@@H](C=C)C(O[C@H]3O[C@@H](CO)[C@H](O)[C@@H](O)[C@@H]3O)OC=C2C(=O)O1
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 540.56 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Amin A, Tuenter E, Exarchou V, Upadhyay A, Cos P, Maes L, Apers S, Pieters L. Phytochemical and Pharmacological Investigations on Nymphoides indica Leaf Extracts. Phytother Res. 2016 Oct;30(10):1624-1633. doi: 10.1002/ptr.5663. Epub 2016 Jun 10. PMID: 27282639. 2: Junior P. Weitere untersuchungen zur verteilung und struktur der bitterstoffe von Menyanthes trifoliata [Further investigations regarding distribution and structure of the bitter principles from Menyanthes trifoliata]. Planta Med. 1989 Feb;55(1):83-7. German. doi: 10.1055/s-2006-961835. PMID: 17262264. 3: Kim TY, Lee BS, Jo BG, Heo SP, Jung YS, Kim SN, Kim KH, Yang MH. Iridoid Glycosides and Coumarin Glycoside Derivatives from the Roots of Nymphoides peltata and Their In Vitro Wound Healing Properties. Int J Mol Sci. 2024 Jan 19;25(2):1268. doi: 10.3390/ijms25021268. PMID: 38279268; PMCID: PMC10816987.