MedKoo Cat#: 128727 | Name: SMS121
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

SMS121 is a CD36 inhibitor with a KD values of about 5 µM.

Chemical Structure

SMS121
SMS121
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 128727

Name: SMS121

CAS#: N/A

Chemical Formula: C20H21NO5

Exact Mass: 355.1420

Molecular Weight: 355.39

Elemental Analysis: C, 67.59; H, 5.96; N, 3.94; O, 22.51

Price and Availability

Size Price Availability Quantity
5mg USD 550.00 2 Weeks
25mg USD 950.00 2 Weeks
100mg USD 1,650.00 2 Weeks
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Related CAS #
No Data
Synonym
SMS121; SMS-121; SMS 121
IUPAC/Chemical Name
(E)-2-(4-(3-(4-(dimethylamino)phenyl)-3-oxoprop-1-en-1-yl)-2-methoxyphenoxy)acetic acid
InChi Key
POSPUCADEWJXCE-ONNFQVAWSA-N
InChi Code
InChI=1S/C20H21NO5/c1-21(2)16-8-6-15(7-9-16)17(22)10-4-14-5-11-18(19(12-14)25-3)26-13-20(23)24/h4-12H,13H2,1-3H3,(H,23,24)/b10-4+
SMILES Code
O=C(O)COC1=CC=C(/C=C/C(C2=CC=C(N(C)C)C=C2)=O)C=C1OC
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 355.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Åbacka H, Masoni S, Poli G, Huang P, Gusso F, Granchi C, Minutolo F, Tuccinardi T, Hagström-Andersson AK, Lindkvist-Petersson K. SMS121, a new inhibitor of CD36, impairs fatty acid uptake and viability of acute myeloid leukemia. Sci Rep. 2024 Apr 20;14(1):9104. doi: 10.1038/s41598-024-58689-1. PMID: 38643249; PMCID: PMC11032350.