GPX4 activator 2 is a ligand for glutathione peroxidase 4 (GPX4; Kd = 0.426 µM). It inhibits erastin-induced ferroptosis in HT-1080 fibrosarcoma cells (EC50 = 7.8 µM).
MedKoo Cat#: 128723
Name: GPX4 Activator 2
CAS#: 950365-31-8
Chemical Formula: C20H26N6O2S
Exact Mass: 414.1838
Molecular Weight: 414.53
Elemental Analysis: C, 57.95; H, 6.32; N, 20.27; O, 7.72; S, 7.73
The following data is based on the product molecular weight 414.53 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
