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MedKoo Cat#: 146140 | Name: Fluacrypyrim

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Fluacrypyrim is a synthetic fungicide used to control a wide range of fungal diseases in crops, particularly in agriculture. It works by inhibiting the fungal enzyme succinate dehydrogenase, which is essential for cellular respiration, disrupting the energy production in the fungus and preventing its growth. Fluacrypyrim is effective against various fungal pathogens, including those that cause powdery mildew, rusts, and blights, making it valuable in maintaining crop health. Its selective action against fungi while being less toxic to humans and beneficial organisms makes it an important tool in integrated pest management.

Chemical Structure

Fluacrypyrim
Fluacrypyrim
CAS#229977-93-9

Theoretical Analysis

MedKoo Cat#: 146140

Name: Fluacrypyrim

CAS#: 229977-93-9

Chemical Formula: C20H21F3N2O5

Exact Mass: 426.1400

Molecular Weight: 426.39

Elemental Analysis: C, 56.34; H, 4.96; F, 13.37; N, 6.57; O, 18.76

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Fluacrypyrim;
IUPAC/Chemical Name
methyl (E)-2-(2-(((2-isopropoxy-6-(trifluoromethyl)pyrimidin-4-yl)oxy)methyl)phenyl)-3-methoxyacrylate
InChi Key
MXWAGQASUDSFBG-RVDMUPIBSA-N
InChi Code
1S/C20H21F3N2O5/c1-12(2)30-19-24-16(20(21,22)23)9-17(25-19)29-10-13-7-5-6-8-14(13)15(11-27-3)18(26)28-4/h5-9,11-12H,10H2,1-4H3/b15-11+
SMILES Code
CO\C=C(\C(=O)OC)C1=C(COC2=NC(OC(C)C)=NC(=C2)C(F)(F)F)C=CC=C1
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 426.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Zhang X, Qiao Z, Guan B, Wang F, Shen X, Shu H, Shan Y, Cong Y, Xing S, Yu Z. Fluacrypyrim Protects Hematopoietic Stem and Progenitor Cells against Irradiation via Apoptosis Prevention. Molecules. 2024 Feb 9;29(4):816. doi: 10.3390/molecules29040816. PMID: 38398568; PMCID: PMC10893289. 2: Yu ZY, Huang R, Xiao H, Sun WF, Shan YJ, Wang B, Zhao TT, Dong B, Zhao ZH, Liu XL, Wang SQ, Yang RF, Luo QL, Cong YW. Fluacrypyrim, a novel STAT3 activation inhibitor, induces cell cycle arrest and apoptosis in cancer cells harboring constitutively-active STAT3. Int J Cancer. 2010 Sep 1;127(6):1259-70. doi: 10.1002/ijc.25169. PMID: 20087863. 3: Ban Y, Morita Y, Ogawa M, Higashi K, Nakatsuka T, Nishihara M, Nakayama M. Inhibition of post-transcriptional gene silencing of chalcone synthase genes in petunia picotee petals by fluacrypyrim. J Exp Bot. 2019 Mar 11;70(5):1513-1523. doi: 10.1093/jxb/erz009. PMID: 30690559. 4: Sakuda S, Prabowo DF, Takagi K, Shiomi K, Mori M, Ōmura S, Nagasawa H. Inhibitory effects of respiration inhibitors on aflatoxin production. Toxins (Basel). 2014 Mar 26;6(4):1193-200. doi: 10.3390/toxins6041193. PMID: 24674936; PMCID: PMC4014728. 5: Luo L, Bo H, Bi Y, Wu Y. [Determination of fluoxastrobin and fluacrypyrim residues in fruits and beverages by ultra performance liquid chromatograph]. Se Pu. 2009 Mar;27(2):201-5. Chinese. PMID: 19626849. 6: Li Z, Wang L, Cong Y, Guo L, Lin X, Yu Z, Wu X, Dong J, Yang R, Cong Y. Flucrypyrim, a novel uterine relaxant, has antinociceptive and anti-inflammatory effects in vivo. Sci Rep. 2017 Feb 21;7:42040. doi: 10.1038/srep42040. PMID: 28220794; PMCID: PMC5318994. 7: Van Nieuwenhuyse P, Van Leeuwen T, Khajehali J, Vanholme B, Tirry L. Mutations in the mitochondrial cytochrome b of Tetranychus urticae Koch (Acari: Tetranychidae) confer cross-resistance between bifenazate and acequinocyl. Pest Manag Sci. 2009 Apr;65(4):404-12. doi: 10.1002/ps.1705. PMID: 19165831. 8: Liu A, Wang X, Chen C, Pei H, Mao C, Wang Y, He H, Huang L, Liu X, Hu Z, Ou X, Huang M, Yao J. The discovery of HNPC-A3066: a novel strobilurin acaricide. Pest Manag Sci. 2009 Mar;65(3):229-34. doi: 10.1002/ps.1673. PMID: 19115224. 9: Chang C, Chen M, Gao J, Luo J, Wu K, Dong T, Zhou K, He X, Hu W, Wu W, Lu C, Hang B, Meeker JD, Wang X, Xia Y. Current pesticide profiles in blood serum of adults in Jiangsu Province of China and a comparison with other countries. Environ Int. 2017 May;102:213-222. doi: 10.1016/j.envint.2017.03.004. Epub 2017 Mar 9. PMID: 28284820. 10: Chai BS, Liu CL, Li HC, Zhang H, Liu SW, Huang G, Chang JB. The discovery of SYP-10913 and SYP-11277: novel strobilurin acaricides. Pest Manag Sci. 2011 Sep;67(9):1141-6. doi: 10.1002/ps.2164. Epub 2011 Mar 30. PMID: 21452169. 11: Hao S, Cai Z, Cao Y, Du X. Design, Synthesis, and Acaricidal Activity of Phenyl Methoxyacrylates Containing 2-Alkenylthiopyrimidine. Molecules. 2020 Jul 25;25(15):3379. doi: 10.3390/molecules25153379. PMID: 32722453; PMCID: PMC7435930.