MedKoo Cat#: 146129 | Name: Pivcefalexin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Pivcefalexin is a prodrug form of cephalexin, a first-generation cephalosporin antibiotic used to treat bacterial infections. It is converted into its active form, cephalexin, after being absorbed in the body. Pivcefalexin works by inhibiting bacterial cell wall synthesis through binding to penicillin-binding proteins, leading to the disruption of cell wall integrity and causing bacterial cell death.

Chemical Structure

Pivcefalexin
Pivcefalexin
CAS#63836-75-9

Theoretical Analysis

MedKoo Cat#: 146129

Name: Pivcefalexin

CAS#: 63836-75-9

Chemical Formula: C22H27N3O6S

Exact Mass: 461.1621

Molecular Weight: 461.53

Elemental Analysis: C, 57.25; H, 5.90; N, 9.10; O, 20.80; S, 6.95

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Pivcefalexin;
IUPAC/Chemical Name
(pivaloyloxy)methyl (6R,7R)-7-((R)-2-amino-2-phenylacetamido)-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
InChi Key
DIGADQKVPFDJSI-SPYBWZPUSA-N
InChi Code
1S/C22H27N3O6S/c1-12-10-32-19-15(24-17(26)14(23)13-8-6-5-7-9-13)18(27)25(19)16(12)20(28)30-11-31-21(29)22(2,3)4/h5-9,14-15,19H,10-11,23H2,1-4H3,(H,24,26)/t14-,15-,19-/m1/s1
SMILES Code
[H][C@]12SCC(C)=C(N1C(=O)[C@H]2NC(=O)[C@H](N)C3=CC=CC=C3)C(=O)OCOC(=O)C(C)(C)C
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 461.53 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Panariello S, Tomasillo MR. L'impiego di un nuovo antibiotico (pivalexina) nel trattamento della mastite puerperale [The use of a new antibiotic (pivalexin) in the treatment of puerperal mastitis]. Arch Ostet Ginecol. 1980 Jul-Aug;85(4):335-8. Italian. PMID: 7201311. 2: Vittorini C, Vacca U, Foresta P, Corsi M, Longo P. Controlled assessment of the concentrations of a new cephalosporin in bile and gallbladder. Arzneimittelforschung. 1981;31(7):1163-5. PMID: 7196766. 3: Crifò S, Foresta P, Corsi M, Andriani G, Sartorelli E. Valutazione comparata della distribuzione di cefalexina nelle tonsille palatine e nel secreto nasale dopo somministrazione de pivalexina e cefalexina [Comparative evaluation of the distribution of cefalexin in the palatine tonsil and in nasal secretions after pivalexine and cefalexin administration]. G Ital Chemioter. 1979 Jan- Dec;26(1-2):363-6. Italian. PMID: 554825.