MedKoo Cat#: 146110 | Name: Asperflavin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Asperflavin is a bioactive compound isolated from the fungus Aspergillus terreus, known for its antioxidant, antimicrobial, and anticancer properties. It works by modulating various cellular pathways, including inhibiting oxidative stress and promoting apoptosis in cancer cells, thereby exerting its therapeutic effects. Asperflavin has been explored for potential applications in treating conditions like cancer, infections, and inflammation.

Chemical Structure

Asperflavin
Asperflavin
CAS#1415764-41-8

Theoretical Analysis

MedKoo Cat#: 146110

Name: Asperflavin

CAS#: 1415764-41-8

Chemical Formula: C16H16O5

Exact Mass: 288.0998

Molecular Weight: 288.30

Elemental Analysis: C, 66.66; H, 5.59; O, 27.75

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Asperflavin;
IUPAC/Chemical Name
(S)-3,6,9-trihydroxy-8-methoxy-3-methyl-3,4-dihydroanthracen-1(2H)-one
InChi Key
WCRDTBIKDNWXLR-INIZCTEOSA-N
InChi Code
1S/C16H16O5/c1-16(20)6-9-3-8-4-10(17)5-12(21-2)14(8)15(19)13(9)11(18)7-16/h3-5,17,19-20H,6-7H2,1-2H3/t16-/m0/s1
SMILES Code
COC1=C2C(O)=C3C(=O)C[C@@](C)(O)CC3=CC2=CC(O)=C1
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 288.30 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Yang X, Kang MC, Li Y, Kim EA, Kang SM, Jeon YJ. Asperflavin, an Anti- Inflammatory Compound Produced by a Marine-Derived Fungus, Eurotium amstelodami. Molecules. 2017 Oct 29;22(11):1823. doi: 10.3390/molecules22111823. PMID: 29109367; PMCID: PMC6150366. 2: Li Y, Li X, Lee U, Kang JS, Choi HD, Sona BW. A new radical scavenging anthracene glycoside, asperflavin ribofuranoside, and polyketides from a marine isolate of the fungus microsporum. Chem Pharm Bull (Tokyo). 2006 Jun;54(6):882-3. doi: 10.1248/cpb.54.882. PMID: 16755063. 3: Grove JF. New metabolic products of Aspergillus flavus. II. Asperflavin, anhydroasperflavin, and 5,7-dihydroxy-4-methylphthalide. J Chem Soc Perkin 1. 1972;19:2406-11. doi: 10.1039/p19720002406. PMID: 4629904. 4: Falade AO, Adewole KE, Ishola AA, Gyebi GA, Olajide NR. Computational studies on the cholinesterase, beta-secretase 1 (BACE1) and monoamine oxidase (MAO) inhibitory activities of endophytes-derived compounds: towards discovery of novel neurotherapeutics. J Biomol Struct Dyn. 2023 Apr;41(6):2540-2554. doi: 10.1080/07391102.2022.2035255. Epub 2022 Feb 4. PMID: 35118932. 5: Fujimoto H, Fujimaki T, Okuyama E, Yamazaki M. Immunomodulatory constituents from an ascomycete, Microascus tardifaciens. Chem Pharm Bull (Tokyo). 1999 Oct;47(10):1426-32. doi: 10.1248/cpb.47.1426. PMID: 10553639. 6: Li DL, Li XM, Wang BG. Natural anthraquinone derivatives from a marine mangrove plant-derived endophytic fungus Eurotium rubrum: structural elucidation and DPPH radical scavenging activity. J Microbiol Biotechnol. 2009 Jul;19(7):675-80. PMID: 19652514.