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MedKoo Cat#: 146107 | Name: Stypotriol

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Stypotriol is a synthetic compound with potential applications in the treatment of inflammatory and autoimmune disorders. It works by modulating the activity of specific enzymes and receptors involved in immune cell signaling, particularly targeting pathways related to the inflammatory response. Its mechanism involves the inhibition of pro-inflammatory cytokine production and the regulation of immune cell activation, which helps reduce inflammation.

Chemical Structure

Stypotriol
Stypotriol
CAS#71106-25-7

Theoretical Analysis

MedKoo Cat#: 146107

Name: Stypotriol

CAS#: 71106-25-7

Chemical Formula: C27H40O4

Exact Mass: 428.2927

Molecular Weight: 428.61

Elemental Analysis: C, 75.66; H, 9.41; O, 14.93

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Stypotriol;
IUPAC/Chemical Name
(2S,2'S,4a'R,4b'S,7'S,8a'R,10a'R)-2',4b',7,8',8',10a'-hexamethyl-3',4',4a',4b',5',6',7',8',8a',9',10',10a'-dodecahydro-2'H,3H-spiro[benzofuran-2,1'-phenanthrene]-4,5,7'-triol
InChi Key
HJSZCMVJNUBOQM-JZFVXYNCSA-N
InChi Code
1S/C27H40O4/c1-15-13-18(28)22(30)17-14-27(31-23(15)17)16(2)7-8-20-25(5)11-10-21(29)24(3,4)19(25)9-12-26(20,27)6/h13,16,19-21,28-30H,7-12,14H2,1-6H3/t16-,19-,20+,21-,25-,26+,27-/m0/s1
SMILES Code
[H][C@@]12CC[C@]3(C)[C@]([H])(CC[C@H](C)[C@@]34CC5=C(O)C(O)=CC(C)=C5O4)[C@@]1(C)CC[C@H](O)C2(C)C
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 428.61 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Pereira DM, Cheel J, Areche C, San-Martin A, Rovirosa J, Silva LR, Valentao P, Andrade PB. Anti-proliferative activity of meroditerpenoids isolated from the brown alga Stypopodium flabelliforme against several cancer cell lines. Mar Drugs. 2011;9(5):852-862. doi: 10.3390/md9050852. Epub 2011 May 13. PMID: 21673894; PMCID: PMC3111187. 2: Hay ME, Fenical W, Gustafson K. Chemical Defense Against Diverse Coral-Reef Herbivores. Ecology. 1987 Dec;68(6):1581-1591. doi: 10.2307/1939850. PMID: 29357158. 3: Muñoz MA, Areche C, San-Martín A, Rovirosa J, Joseph-Nathan P. VCD determination of the absolute configuration of stypotriol. Nat Prod Commun. 2009 Aug;4(8):1037-40. PMID: 19768979. 4: Gil B, Ferrándiz ML, Sanz MJ, Terencio MC, Ubeda A, Rovirosa J, San-Martin A, Alcaraz MJ, Payá M. Inhibition of inflammatory responses by epitaondiol and other marine natural products. Life Sci. 1995;57(2):PL25-30. doi: 10.1016/0024-3205(95)00260-d. PMID: 7603289. 5: Areche C, San-Martín A, Rovirosa J, Soto-Delgado J, Contreras R. An unusual halogenated meroditerpenoid from Stypopodium flabelliforme: studies by NMR spectroscopic and computational methods. Phytochemistry. 2009 Jul;70(10):1315-20. doi: 10.1016/j.phytochem.2009.07.017. Epub 2009 Aug 19. PMID: 19698963.