MedKoo Cat#: 146099 | Name: Sincamidine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Sincamidine is a synthetic compound with potential applications in the treatment of hypertension and other cardiovascular conditions. It functions as a selective agonist of the imidazoline receptors, which are involved in regulating blood pressure and sympathetic nervous system activity. By binding to these receptors, sincamidine helps reduce sympathetic outflow, leading to vasodilation and a subsequent decrease in blood pressure.

Chemical Structure

Sincamidine
Sincamidine
CAS#59532-50-2

Theoretical Analysis

MedKoo Cat#: 146099

Name: Sincamidine

CAS#: 59532-50-2

Chemical Formula: C16H27NO5

Exact Mass: 313.1889

Molecular Weight: 313.39

Elemental Analysis: C, 61.32; H, 8.68; N, 4.47; O, 25.53

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
Sincamidine; Epiheliotrine; 1-Epiheliotrine; 7R-Heliotrine; NSC-30620; NSC 30620; NSC30620;
IUPAC/Chemical Name
((1R,7aR)-1-hydroxy-2,3,5,7a-tetrahydro-1H-pyrrolizin-7-yl)methyl (2S,3R)-2-hydroxy-2-isopropyl-3-methoxybutanoate
InChi Key
LMFKRLGHEKVMNT-MEWXFMAXSA-N
InChi Code
1S/C16H27NO5/c1-10(2)16(20,11(3)21-4)15(19)22-9-12-5-7-17-8-6-13(18)14(12)17/h5,10-11,13-14,18,20H,6-9H2,1-4H3/t11-,13-,14-,16+/m1/s1
SMILES Code
[H][C@@]12[C@H](O)CCN1CC=C2COC(=O)[C@](O)(C(C)C)[C@@H](C)OC
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 313.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL