IUPAC/Chemical Name
(9S,10R)-10-ethyl-9-propyl-5,9,10,11-tetrahydro-1H-cyclonona[1,2-c:5,6-c']difuran-1,3,6,8(4H)-tetraone
InChi Key
OJIGDJPKCFGFKH-ZJUUUORDSA-N
InChi Code
1S/C18H20O6/c1-3-5-10-9(4-2)8-13-11(15(19)23-17(13)21)6-7-12-14(10)18(22)24-16(12)20/h9-10H,3-8H2,1-2H3/t9-,10+/m1/s1
SMILES Code
CCC[C@H]1[C@H](CC)CC2=C(CCC3=C1C(=O)OC3=O)C(=O)OC2=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
332.35
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Harms H, Orlikova B, Ji S, Nesaei-Mosaferan D, König GM, Diederich M. Epipolythiodiketopiperazines from the Marine Derived Fungus Dichotomomyces cejpii with NF-κB Inhibitory Potential. Mar Drugs. 2015 Aug 6;13(8):4949-66. doi: 10.3390/md13084949. PMID: 26258781; PMCID: PMC4557009.
2: Crane RI, Hedden P, MacMillan J, Turner WB. Fungal products. IV. The structure of heveadride, a new nonadrede from Helminthosporium heveae. J Chem Soc Perkin 1. 1973;2:194-200. doi: 10.1039/p19730000194. PMID: 4738978.
3: Hosoe T, Fukushima K, Itabashi T, Nozawa K, Takizawa K, Okada K, Takaki GM, Kawai K. A new nonadride derivative, dihydroepiheveadride, as characteristic antifungal agent against filamentous fungi, isolated from unidentified fungus IFM 52672. J Antibiot (Tokyo). 2004 Sep;57(9):573-8. doi: 10.7164/antibiotics.57.573. PMID: 15580958.
