3-O-methyl Estradiol | synthetic estrogen | CAS#1035-77-4

MedKoo Cat#: 128665 | Name: 3-O-methyl Estradiol

Description:

WARNING: This product is for research use only, not for human or veterinary use.

3-O-methyl Estradiol is a synthetic estrogen. It disrupts microtubule networks in V79 Chinese hamster cells (EC50 = 9 µM) and inhibits the proliferation of the same cells by 92% when used at a concentration of 20 µM.

Chemical Structure

3-O-methyl Estradiol

CAS#1035-77-4

Theoretical Analysis

MedKoo Cat#: 128665

Name: 3-O-methyl Estradiol

CAS#: 1035-77-4

Chemical Formula: C19H26O2

Exact Mass: 286.1933

Molecular Weight: 286.42

Elemental Analysis: C, 79.68; H, 9.15; O, 11.17

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

3-O-methyl Estradiol; Estradiol 3-methyl ether; 3-Methoxyestradiol; 3-O-methyl E2; NSC 58851

IUPAC/Chemical Name

(8R,9S,13S,14S,17S)-3-methoxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-17-ol

InChi Key

ULAADVBNYHGIBP-GFEQUFNTSA-N

InChi Code

InChI=1S/C19H26O2/c1-19-10-9-15-14-6-4-13(21-2)11-12(14)3-5-16(15)17(19)7-8-18(19)20/h4,6,11,15-18,20H,3,5,7-10H2,1-2H3/t15-,16-,17+,18+,19+/m1/s1

SMILES Code

C[C@@]12[C@](CC[C@@H]2O)([H])[C@@]3([H])[C@@](CC1)([H])C4=CC=C(OC)C=C4CC3

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 286.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Bydal P, Sam KM, Poirier D. Steroid-hindered 17 beta-tertiary alcohol: characterization of dehydrated compounds. Steroids. 1996 Jun;61(6):349-53. doi: 10.1016/0039-128x(96)00036-0. PMID: 8776797.