MY-05 is a MYC inhibitor. MY0 selectively targets c-MYC in cells and disrupts MYC−MAX interaction. MY05 engages intracellular c-MYC, modulates c-MYC thermal stability, reduces c-MYC transcriptional targets, and inhibits proliferation in cancer cells and tumor growth in mice. In summary, we identified a novel compound that directly interacts with c-MYC to disrupt the transcriptional program.
MedKoo Cat#: 128637
Name: MY-05
CAS#: N/A
Chemical Formula: C19H11ClN4O
Exact Mass: 346.0621
Molecular Weight: 346.77
Elemental Analysis: C, 65.81; H, 3.20; Cl, 10.22; N, 16.16; O, 4.61
The following data is based on the product molecular weight 346.77 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
