Cycloprothrin | CAS#63935-38-6 | insecticide

MedKoo Cat#: 146057 | Name: Cycloprothrin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Cycloprothrin is a synthetic insecticide belonging to the class of pyrethroids, commonly used for pest control in agricultural and residential settings. It works by disrupting the nervous system of insects, specifically by interfering with the sodium channels in nerve cells, which leads to prolonged depolarization and paralysis of the insect. This action results in the death of the pest, making cycloprothrin effective against a variety of insects, including mosquitoes, flies, and agricultural pests. Its selective toxicity to insects, coupled with its rapid action, makes it a valuable tool in integrated pest management strategies.

Chemical Structure

Cycloprothrin

CAS#63935-38-6

Theoretical Analysis

MedKoo Cat#: 146057

Name: Cycloprothrin

CAS#: 63935-38-6

Chemical Formula: C26H21Cl2NO4

Exact Mass: 481.0800

Molecular Weight: 482.36

Elemental Analysis: C, 64.74; H, 4.39; Cl, 14.70; N, 2.90; O, 13.27

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Cycloprothrin; NK-8116; NK8116; NK 8116; PHENCYCLATE; GH-414; GH 414; GH414;

IUPAC/Chemical Name

cyano(3-phenoxyphenyl)methyl 2,2-dichloro-1-(4-ethoxyphenyl)cyclopropane-1-carboxylate

InChi Key

CGTWCAVZZBLHQH-UHFFFAOYSA-N

InChi Code

1S/C26H21Cl2NO4/c1-2-31-20-13-11-19(12-14-20)25(17-26(25,27)28)24(30)33-23(16-29)18-7-6-10-22(15-18)32-21-8-4-3-5-9-21/h3-15,23H,2,17H2,1H3

SMILES Code

CCOC1=CC=C(C=C1)C2(CC2(Cl)Cl)C(=O)OC(C#N)C3=CC(OC4=CC=CC=C4)=CC=C3

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 482.36 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Jiang B, Wang H, Fu QM, Li ZY. The chiral pyrethroid cycloprothrin: stereoisomer synthesis and separation and stereoselective insecticidal activity. Chirality. 2008 Feb;20(2):96-102. doi: 10.1002/chir.20508. PMID: 18072265. 2: Du G, Shen O, Sun H, Fei J, Lu C, Song L, Xia Y, Wang S, Wang X. Assessing hormone receptor activities of pyrethroid insecticides and their metabolites in reporter gene assays. Toxicol Sci. 2010 Jul;116(1):58-66. doi: 10.1093/toxsci/kfq120. Epub 2010 Apr 21. PMID: 20410157. 3: Lummis SC, Chow SC, Holan G, Johnston GA. gamma-Aminobutyric acid receptor ionophore complexes: differential effects of deltamethrin, dichlorodiphenyltrichloroethane, and some novel insecticides in a rat brain membrane preparation. J Neurochem. 1987 Mar;48(3):689-94. doi: 10.1111/j.1471-4159.1987.tb05571.x. PMID: 3027258. 4: Sales N, Levot GW, Hughes PB. Monitoring and selection of resistance to pyrethroids in the Australian sheep blowfly, Lucilia cuprina. Med Vet Entomol. 1989 Jul;3(3):287-91. doi: 10.1111/j.1365-2915.1989.tb00230.x. PMID: 2519674. 5: Nakata M, Fukushima A, Ohkawa H. A monoclonal antibody-based ELISA for the analysis of the insecticide flucythrinate in environmental and crop samples. Pest Manag Sci. 2001 Mar;57(3):269-77. doi: 10.1002/ps.286. PMID: 11455657.