MedKoo Cat#: 146056 | Name: Lasiol

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Lasiol is a naturally occurring compound found in various plant species, particularly in the Lasiocarpus genus, with known antimicrobial and anti-inflammatory properties. It works by inhibiting key enzymes involved in the inflammatory response and by reducing the production of pro-inflammatory cytokines. This makes lasiol useful in the treatment of conditions characterized by excessive inflammation and infection. Additionally, lasiol's antimicrobial effects suggest its potential as a natural agent for combating bacterial and fungal infections, making it valuable for both medicinal and therapeutic applications.

Chemical Structure

Lasiol
Lasiol
CAS#131479-19-1

Theoretical Analysis

MedKoo Cat#: 146056

Name: Lasiol

CAS#: 131479-19-1

Chemical Formula: C10H20O

Exact Mass: 156.1500

Molecular Weight: 156.27

Elemental Analysis: C, 76.86; H, 12.90; O, 10.24

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Lasiol;
IUPAC/Chemical Name
(2S,3S)-2,3,6-trimethylhept-5-en-1-ol
InChi Key
NEFLTGMRGQSVHM-VHSXEESVSA-N
InChi Code
1S/C10H20O/c1-8(2)5-6-9(3)10(4)7-11/h5,9-11H,6-7H2,1-4H3/t9-,10+/m0/s1
SMILES Code
C[C@H](CO)[C@@H](C)CC=C(C)C
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 156.27 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Skotnitzki J, Spessert L, Knochel P. Regio- and Stereoselective Allylic Substitutions of Chiral Secondary Alkylcopper Reagents: Total Synthesis of (+)-Lasiol, (+)-13-Norfaranal, and (+)-Faranal. Angew Chem Int Ed Engl. 2019 Jan 28;58(5):1509-1514. doi: 10.1002/anie.201811330. Epub 2018 Dec 28. PMID: 30380160. 2: Kasai T, Watanabe H, Mori K. Synthesis of the enantiomers of lasiol, an acyclic monoterpene alcohol in the mandibular gland secretion of the male ants, Lasius meridionalis. Bioorg Med Chem. 1993 Jul;1(1):67-70. doi: 10.1016/s0968-0896(00)82104-5. PMID: 8081839. 3: Morozova V, Moriya K, Mayer P, Knochel P. Stereoselective Synthesis and Retentive Trapping of α-Chiral Secondary Alkyllithiums Leading to Stereodefined α,β-Dimethyl Carboxylic Esters. Chemistry. 2016 Jul 11;22(29):9962-5. doi: 10.1002/chem.201601911. Epub 2016 Jun 8. PMID: 27140953. 4: van Zijl AW, Szymanski W, López F, Minnaard AJ, Feringa BL. Catalytic enantioselective synthesis of vicinal dialkyl arrays. J Org Chem. 2008 Sep 19;73(18):6994-7002. doi: 10.1021/jo8010649. Epub 2008 Aug 7. PMID: 18683977.