MedKoo Cat#: 146042 | Name: Cassamine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Cassamine is a naturally occurring alkaloid compound found in plants, particularly in the Cassia genus, and is known for its potential medicinal properties. It exhibits anti-inflammatory, antimicrobial, and antioxidant effects by modulating various biochemical pathways in the body. Cassamine works by inhibiting the production of pro-inflammatory cytokines and free radicals, which can reduce inflammation and oxidative stress. Due to these properties, it has been explored for applications in treating conditions such as infections, inflammatory disorders, and possibly some forms of cancer.

Chemical Structure

Cassamine
Cassamine
CAS#471-71-6

Theoretical Analysis

MedKoo Cat#: 146042

Name: Cassamine

CAS#: 471-71-6

Chemical Formula: C25H39NO5

Exact Mass: 433.2800

Molecular Weight: 433.59

Elemental Analysis: C, 69.25; H, 9.07; N, 3.23; O, 18.45

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Cassamine; Cassamin;
IUPAC/Chemical Name
methyl (1S,4aR,4bS,8R,8aS,10aR,E)-7-(2-(2-(dimethylamino)ethoxy)-2-oxoethylidene)-1,4a,8-trimethyl-9-oxotetradecahydrophenanthrene-1-carboxylate
InChi Key
RUABDWHGFBIFOR-AOIDQDHJSA-N
InChi Code
1S/C25H39NO5/c1-16-17(14-21(28)31-13-12-26(4)5)8-9-18-22(16)19(27)15-20-24(18,2)10-7-11-25(20,3)23(29)30-6/h14,16,18,20,22H,7-13,15H2,1-6H3/b17-14+/t16-,18-,20+,22-,24+,25-/m0/s1
SMILES Code
[H][C@]12CC\C([C@H](C)[C@]1([H])C(=O)C[C@@]3([H])[C@](C)(CCC[C@]23C)C(=O)OC)=C/C(=O)OCCN(C)C
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 433.59 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: MATHIESON DW, JAQUES B, CHAMPMAN GT, ARYA VP, ENGEL BG. The structure of cassamine and erythrophlamine. Experientia. 1960 Sep 15;16:404-6. doi: 10.1007/BF02178832. PMID: 13768118. 2: Ngo TC, Nguyen TH, Dao DQ. Radical Scavenging Activity of Natural-Based Cassaine Diterpenoid Amides and Amines. J Chem Inf Model. 2019 Feb 25;59(2):766-776. doi: 10.1021/acs.jcim.8b00847. Epub 2019 Feb 6. PMID: 30681326. 3: Konan JD, Attioua BK, Kabran FA, Ahmont Kablan CL, Koffi AA, Any-Grah SA, Sissouma D, Seon-Meniel B, LeBlanc K, Jullian JC, Beniddir MA, Champy P. Spectroscopic data of new cassane diterpenoids from the root bark of Erythrophleum suaveolens. Data Brief. 2019 Jul 31;25:104315. doi: 10.1016/j.dib.2019.104315. PMID: 31453295; PMCID: PMC6700417.