MedKoo Cat#: 146024 | Name: AM-1221

Description:

WARNING: This product is for research use only, not for human or veterinary use.

AM-1221 is a selective small molecule compound primarily investigated for its potential in treating neurological and psychiatric disorders. It functions as an agonist for the 5-HT1A receptor, a subtype of serotonin receptor, which plays a key role in mood regulation, anxiety, and depression. By stimulating these receptors, AM-1221 can modulate serotonin levels in the brain, leading to anxiolytic and antidepressant effects. Its mechanism of action involves enhancing serotonin transmission and balancing neural activity, making it a promising candidate for conditions like anxiety and depression.

Chemical Structure

AM-1221
AM-1221
CAS#335160-53-7

Theoretical Analysis

MedKoo Cat#: 146024

Name: AM-1221

CAS#: 335160-53-7

Chemical Formula: C27H27N3O3

Exact Mass: 441.2100

Molecular Weight: 441.53

Elemental Analysis: C, 73.45; H, 6.16; N, 9.52; O, 10.87

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
AM-1221; AM1221; AM 1221;
IUPAC/Chemical Name
(2-methyl-1-((1-methylpiperidin-2-yl)methyl)-6-nitro-1H-indol-3-yl)(naphthalen-1-yl)methanone
InChi Key
QGNIEJBBHMMNOZ-UHFFFAOYSA-N
InChi Code
1S/C27H27N3O3/c1-18-26(27(31)23-12-7-9-19-8-3-4-11-22(19)23)24-14-13-20(30(32)33)16-25(24)29(18)17-21-10-5-6-15-28(21)2/h3-4,7-9,11-14,16,21H,5-6,10,15,17H2,1-2H3
SMILES Code
CN1CCCCC1CN2C(C)=C(C(=O)C3=CC=CC4=CC=CC=C34)C5=C2C=C(C=C5)[N+]([O-])=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 441.53 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL