MedKoo Cat#: 128588 | Name: ART26.12
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

ART26.12 is an orally active FABP5 inhibitor with anti-cannabinoid properties.

Chemical Structure

ART26.12
CAS#2766800-24-0

Theoretical Analysis

MedKoo Cat#: 128588

Name: ART26.12

CAS#: 2766800-24-0

Chemical Formula: C29H28O6

Exact Mass: 472.1886

Molecular Weight: 472.54

Elemental Analysis: C, 73.71; H, 5.97; O, 20.31

Price and Availability

Size Price Availability Quantity
5mg USD 450.00 2 Weeks
25mg USD 950.00 2 Weeks
100mg USD 1,650.00 2 Weeks
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Related CAS #
No Data
Synonym
ART26.12; ART2612; ART-26.12
IUPAC/Chemical Name
(1R,2R,3R,4R)-3-(((2,3-dihydro-1H-inden-2-yl)oxy)carbonyl)-2,4-bis(2-methoxyphenyl)cyclobutane-1-carboxylic acid
InChi Key
HFKXLDACQCGGEI-FPCALVHFSA-N
InChi Code
InChI=1S/C29H28O6/c1-33-22-13-7-5-11-20(22)24-26(28(30)31)25(21-12-6-8-14-23(21)34-2)27(24)29(32)35-19-15-17-9-3-4-10-18(17)16-19/h3-14,19,24-27H,15-16H2,1-2H3,(H,30,31)/t24-,25-,26-,27-/m1/s1
SMILES Code
O=C([C@H]1[C@H](C2=C(C=CC=C2)OC)[C@@H]([C@H]1C3=C(C=CC=C3)OC)C(O)=O)OC4CC5=CC=CC=C5C4
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 472.54 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Warren G, Osborn M, Tsantoulas C, David-Pereira A, Cohn D, Duffy P, Ruston L, Johnson C, Bradshaw H, Kaczocha M, Ojima I, Yates A, O'Sullivan SE. Discovery and Preclinical Evaluation of a Novel Inhibitor of FABP5, ART26.12, Effective in Oxaliplatin-Induced Peripheral Neuropathy. J Pain. 2024 Jul;25(7):104470. doi: 10.1016/j.jpain.2024.01.335. Epub 2024 Jan 15. PMID: 38232863.