MedKoo Cat#: 145999 | Name: Filiformin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Filiformin is a natural compound found in certain plants, known for its potential anti-inflammatory and antioxidant properties. It works by modulating cellular pathways that regulate oxidative stress and inflammation, potentially reducing tissue damage and supporting overall health. The mechanism of filiformin involves the inhibition of pro-inflammatory cytokines and enzymes involved in oxidative damage, which can contribute to its protective effects. Its applications are being explored in treating chronic inflammatory conditions, such as arthritis and cardiovascular diseases, as well as in promoting general well-being through its antioxidative effects.

Chemical Structure

Filiformin
Filiformin
CAS#62311-75-5

Theoretical Analysis

MedKoo Cat#: 145999

Name: Filiformin

CAS#: 62311-75-5

Chemical Formula: C15H19BrO

Exact Mass: 294.0600

Molecular Weight: 295.22

Elemental Analysis: C, 61.03; H, 6.49; Br, 27.07; O, 5.42

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Filiformin;
IUPAC/Chemical Name
(2S,5R,10R)-7-bromo-2,5,8,10-tetramethyl-2,3,4,5-tetrahydro-2,5-methanobenzo[b]oxepine
InChi Key
KUYRIOUUTKXVSM-KMUNFCNLSA-N
InChi Code
1S/C15H19BrO/c1-9-7-13-11(8-12(9)16)14(3)5-6-15(4,17-13)10(14)2/h7-8,10H,5-6H2,1-4H3/t10-,14-,15+/m1/s1
SMILES Code
[H][C@]1(C)[C@]2(C)CC[C@@]1(C)C3=C(O2)C=C(C)C(Br)=C3
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 295.22 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Gochfeld DJ, Hamann MT. Isolation and biological evaluation of filiformin, plakortide F, and plakortone G from the Caribbean sponge Plakortis sp. J Nat Prod. 2001 Nov;64(11):1477-9. doi: 10.1021/np010216u. PMID: 11720540. 2: Blair DJ, Fletcher CJ, Wheelhouse KM, Aggarwal VK. Stereocontrolled synthesis of adjacent acyclic quaternary-tertiary motifs: application to a concise total synthesis of (-)-filiformin. Angew Chem Int Ed Engl. 2014 May 26;53(22):5552-5. doi: 10.1002/anie.201400944. Epub 2014 Apr 22. PMID: 24757079. 3: Nemoto H. Synthetic organic chemistry based on small ring compounds. Chem Pharm Bull (Tokyo). 2007 Jul;55(7):961-74. doi: 10.1248/cpb.55.961. PMID: 17603183. 4: Nath A, Mal J, Venkateswaran RV. A Facile, Expeditious Route to the Benzooxabicyclo[3.2.1]octane System. Application to a Short, High-Yield Synthesis of Filiformin. J Org Chem. 1996 Jun 26;61(13):4391-4394. doi: 10.1021/jo952184j. PMID: 11667342. 5: Dias DA, White JM, Urban S. Laurencia filiformis: phytochemical profiling by conventional and HPLC-NMR approaches. Nat Prod Commun. 2009 Feb;4(2):157-72. PMID: 19370917.