MedKoo Cat#: 145993 | Name: R-7277

Description:

WARNING: This product is for research use only, not for human or veterinary use.

R-7277 is a synthetic compound known for its potential as a selective inhibitor of the serotonin transporter (SERT). It works by blocking the reuptake of serotonin in the brain, which increases the levels of this neurotransmitter in the synaptic cleft, potentially enhancing mood and cognitive function. R-7277 has been studied primarily for its applications in the treatment of depression, anxiety disorders, and other mood-related conditions. Its mechanism of action makes it similar to other selective serotonin reuptake inhibitors (SSRIs), though its specific properties may offer distinct therapeutic benefits.

Chemical Structure

R-7277
R-7277
CAS#530141-72-1

Theoretical Analysis

MedKoo Cat#: 145993

Name: R-7277

CAS#: 530141-72-1

Chemical Formula: C29H27NO8

Exact Mass: 517.1700

Molecular Weight: 517.53

Elemental Analysis: C, 67.30; H, 5.26; N, 2.71; O, 24.73

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
R-7277; R 7277; R7277; T5224; T-5224;
IUPAC/Chemical Name
3-(5-(4-(cyclopentyloxy)-2-hydroxybenzoyl)-2-((3-oxo-2,3-dihydrobenzo[d]isoxazol-6-yl)methoxy)phenyl)propanoic acid
InChi Key
DALCQQSLNPLQFZ-UHFFFAOYSA-N
InChi Code
1S/C29H27NO8/c31-24-15-21(37-20-3-1-2-4-20)8-10-22(24)28(34)19-6-11-25(18(14-19)7-12-27(32)33)36-16-17-5-9-23-26(13-17)38-30-29(23)35/h5-6,8-11,13-15,20,31H,1-4,7,12,16H2,(H,30,35)(H,32,33)
SMILES Code
OC(=O)CCC1=C(OCC2=CC=C3C(=O)NOC3=C2)C=CC(=C1)C(=O)C4=C(O)C=C(OC5CCCC5)C=C4
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 517.53 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL