MedKoo Cat#: 128553 | Name: THIQ
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

THIQ is a melanocortin-4 receptor (MC4R) agonist that is selective over MC1R, MC3R, and MC5R human receptors expressed in CHO cells (IC50s = 1.2, 2,067, 761, and 326 nM, respectively).

Chemical Structure

THIQ
THIQ
CAS#312637-48-2

Theoretical Analysis

MedKoo Cat#: 128553

Name: THIQ

CAS#: 312637-48-2

Chemical Formula: C33H41ClN6O2

Exact Mass: 588.2980

Molecular Weight: 589.18

Elemental Analysis: C, 67.27; H, 7.01; Cl, 6.02; N, 14.26; O, 5.43

Price and Availability

Size Price Availability Quantity
1mg USD 350.00 2 Weeks
5mg USD 650.00 2 Weeks
10mg USD 950.00 2 Weeks
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Related CAS #
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Synonym
THIQ
IUPAC/Chemical Name
(R)-N-((R)-1-(4-((1H-1,2,4-triazol-1-yl)methyl)-4-cyclohexylpiperidin-1-yl)-3-(4-chlorophenyl)-1-oxopropan-2-yl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide
InChi Key
HLCHESOMJVGDSJ-LOYHVIPDSA-N
InChi Code
InChI=1S/C33H41ClN6O2/c34-28-12-10-24(11-13-28)18-30(38-31(41)29-19-25-6-4-5-7-26(25)20-36-29)32(42)39-16-14-33(15-17-39,21-40-23-35-22-37-40)27-8-2-1-3-9-27/h4-7,10-13,22-23,27,29-30,36H,1-3,8-9,14-21H2,(H,38,41)/t29-,30-/m1/s1
SMILES Code
O=C(N[C@H](CC1=CC=C(Cl)C=C1)C(N2CCC(CN3C=NC=N3)(C4CCCCC4)CC2)=O)[C@@H]5NCC6=CC=CC=C6C5
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 589.18 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL