Thiooxacillin is a semisynthetic beta-lactam antibiotic derived from oxacillin, with enhanced activity against certain bacterial strains, particularly methicillin-resistant Staphylococcus aureus (MRSA). Its mechanism of action involves inhibiting bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), preventing the final cross-linking step of peptidoglycan, which is essential for bacterial cell wall integrity. Thiooxacillin is used in the treatment of various bacterial infections, including skin and soft tissue infections, respiratory tract infections, and infections caused by resistant bacterial strains. Its ability to target resistant bacteria makes it a valuable option in combating multi-drug-resistant infections.
MedKoo Cat#: 145975
Name: Thiooxacillin
CAS#: 5053-35-0
Chemical Formula: C19H19N3O4S2
Exact Mass: 417.0800
Molecular Weight: 417.50
Elemental Analysis: C, 54.66; H, 4.59; N, 10.06; O, 15.33; S, 15.36
The following data is based on the product molecular weight 417.50 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
