MedKoo Cat#: 145973 | Name: Parsonine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Parsonine is a naturally occurring alkaloid derived from the plant Lobelia species, known for its potential biological activities. It has shown promise in the treatment of various health conditions, particularly for its neurotoxic effects, which can be leveraged in targeted treatments for certain diseases. The compound acts by inhibiting the activity of acetylcholinesterase, thereby increasing acetylcholine levels and potentially enhancing cognitive function. Additionally, parsonine has been studied for its antimicrobial properties, showing effectiveness in inhibiting bacterial growth, making it a candidate for use in developing antimicrobial agents.

Chemical Structure

Parsonine
Parsonine
CAS#72213-98-0

Theoretical Analysis

MedKoo Cat#: 145973

Name: Parsonine

CAS#: 72213-98-0

Chemical Formula: C22H33NO8

Exact Mass: 439.2200

Molecular Weight: 439.51

Elemental Analysis: C, 60.12; H, 7.57; N, 3.19; O, 29.12

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Parsonine;
IUPAC/Chemical Name
(3S,7R,8S,11a1R,16aR)-3,8-dihydroxy-3,8-diisopropyl-7-methyl-3,4,11,11a1,13,15,16,16a-octahydro-7H-[1,5,10]trioxacyclotetradecino[7,8,9-gh]pyrrolizine-2,5,9(8H)-trione
InChi Key
MPPSDVYCCOJJIB-QCNRXRGQSA-N
InChi Code
1S/C22H33NO8/c1-12(2)21(27)10-17(24)30-14(5)22(28,13(3)4)20(26)29-11-15-6-8-23-9-7-16(18(15)23)31-19(21)25/h6,12-14,16,18,27-28H,7-11H2,1-5H3/t14-,16-,18-,21+,22+/m1/s1
SMILES Code
[H][C@]12CCN3CC=C(COC(=O)[C@](O)(C(C)C)[C@@H](C)OC(=O)C[C@](O)(C(C)C)C(=O)O1)[C@]23[H]
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 439.51 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Hartmann T, Theuring C, Witte L, Schulz S, Pasteels JM. Biochemical processing of plant acquired pyrrolizidine alkaloids by the neotropical leaf- beetle Platyphora boucardi. Insect Biochem Mol Biol. 2003 May;33(5):515-23. doi: 10.1016/s0965-1748(03)00026-2. PMID: 12706631.